Pemphigus vegetans

Pemphigus vegetans
Clinical presentation indicating- Irregular, hypertrophic, fissured plaque
See also: List of target antigens in pemphigus

Pemphigus vegetans (PV) is a localized form of pemphigus vulgaris.[1]

Definition and types

PV is a localized form of pemphigus vulgaris.[1] in which there is a localized vegetating papillomatous response. The eroded areas do not heal like usual but form papillomatous growth and vegetation.

Two forms are recognized:

  • Pemphigus vegetans of Neumann is a localized disease of pemphigus vulgaris slightly more extensive than pemphigus vegetans of Hallopeau.[2] : 568  This type is more common and characterized by early lesions similar to Pemphigus Vulgaris with large bullae and erosive areas. Healing is through formation of granulation tissue. It is named for the Austrian Dermatologist, Isidor Neumann.
  • Pemphigus vegetans of Hallopeau is a disease of localized pemphigus vulgaris.[2] : 568  It is named for François Henri Hallopeau. This type is less aggressive and has pustules not bullae. These pustules heal by verrucous hyperkeratotic vegetations.

Epidemiology

Accounts for 1-2% of pemphigus cases and is a relatively benign variant of pemphigus vulgaris.

See also

References

  1. 1 2 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "21. Chronic blistering dermatoses". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 456-457. ISBN 978-0-323-54753-6. Archived from the original on 2022-03-14. Retrieved 2022-03-14.
  2. 1 2 Irwin M. Freedberg; et al., eds. (2003). Fitzpatrick's dermatology in general medicine (6th ed.). New York, NY [u.a.]: McGraw-Hill. p. 558. ISBN 978-0-07-138076-8.
Classification


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