Struma ovarii

Struma ovarii
Micrograph of a struma ovarii. Characteristic thyroid follicles are seen on the right, and ovarian stroma on the left. H&E stain.

A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains mostly thyroid tissue, which may cause hyperthyroidism.[1]

Despite its name, struma ovarii is not restricted to the ovary.

The vast majority of struma ovarii are benign tumours; however, malignant tumours of this type are found in a small percentage of cases.[2]

The ultrasound (US) features of struma ovarii are nonspecific, but a heterogeneous, predominantly solid mass may be seen. US demonstrates a complex appearance with multiple cystic and solid areas, findings that reflect the gross pathologic appearance of the tumor.

Magnetic resonance imaging findings may be more characteristic: The cystic spaces demonstrate both high and low signal intensity on T1- and T2-weighted images. Some of the cystic spaces may demonstrate low signal intensity on both T1- and T2-weighted images due to the thick, gelatinous colloid of the struma. No fat is evident in these lesions.[3]

  • a-c)Immunohistochemical (CK19, galetin-3, HBME-1) staining of malignant struma ovarii tissues
    a-c)Immunohistochemical (CK19, galetin-3, HBME-1) staining of malignant struma ovarii tissues
  • Low magnification Struma ovarii
    Low magnification Struma ovarii
  • High magnification Struma ovarii
    High magnification Struma ovarii

See also

References

  1. ↑ Kim D, Cho HC, Park JW, Lee WA, Kim YM, Chung PS, et al. (March 2009). "Struma ovarii and peritoneal strumosis with thyrotoxicosis". Thyroid. 19 (3): 305–308. doi:10.1089/thy.2008.0307. PMID 19265502.
  2. ↑ Struma Ovarii at eMedicine
  3. ↑ Outwater EK, Siegelman ES, Hunt JL (Mar–Apr 2001). "Ovarian teratomas: tumor types and imaging characteristics". Radiographics. 21 (2): 475–490. doi:10.1148/radiographics.21.2.g01mr09475. PMID 11259710.
Classification
External resources

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