Vaccitech

Vaccitech plc
TypePublic
Traded as
Nasdaq: VACC
IndustryVaccines
Immunotherapy
Biotechnology
Founded2016 (2016)
Founder
  • Sarah Gilbert
  • Adrian V. S. Hill
Headquarters
Oxford Science Park, Oxford
,
United Kingdom
Websitevaccitech.co.uk

Vaccitech plc is a biotechnology company developing vaccines and immunotherapies for infectious diseases and cancer, such as hepatitis B, HPV and prostate cancer.[1][2]

Technology

The company's platform includes Chimpanzee Adenovirus Oxford (ChAdOx) and Modified Vaccinia Ankara (MVA), two viral vectors which safely mimic viral infection in human cells and elicit antibody and T cell responses to pathogens and tumours.[3]

History

The company was founded in 2016 as a University spin-off by Sarah Gilbert and Adrian V. S. Hill at The Jenner Institute, University of Oxford.[4][5][6]

Vaccitech has been financed and supported by Google Ventures (GV), Fosun International, Tencent, Huawei, Sequoia Capital, GeneMatrix, Liontrust Asset Management, Korea Investment Partners and Oxford Sciences Innovation (OSI).[7][8]

In early 2020, Vaccitech and the University of Oxford co-invented a vaccine for COVID-19 using the ChAdOx platform.

COVID-19 vaccine

In July 2020, it was reported that people in Brazil, South Africa and the US had been recruited to populate the vaccine trials.[9]

In July 2020, Vaccitech scientists reported in The Lancet a "single-blind, randomised controlled trial in five trial sites in the UK of a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the SARS-CoV-2 spike protein." Several subjects needed prophylactic paracetamol to minimize their adverse reactions.

References

  1. ↑ Vaccitech on Twitter Edit this at Wikidata
  2. ↑ Anon (2016). "Vaccitech Limited". companieshouse.gov.uk. London: Companies House.
  3. ↑ Anon (2019). "Vaccitech - Creating ways to treat and prevent disease". vaccitech.co.uk. Vaccitech Limited.
  4. ↑ Anon (2019). "Vaccitech Ltd". bloomberg.com. Bloomberg News.
  5. ↑ Anon (2016). "Universal flu vaccine under development by Oxford spinout Vaccitech". ox.ac.uk. University of Oxford.
  6. ↑ Anon (2019). "Vaccitech secures £20m Series A with GV, OSI and Sequoia China". innovation.ox.ac.uk. Oxford University Innovation.
  7. ↑ Anon (2019). "About Vaccitech". vaccitech.co.uk. Vaccitech Limited.
  8. ↑ https://www.theweek.co.uk/107979/inside-the-chinese-companies-produce-the-worlds-first-coronavirus-vaccine
  9. ↑ Boseley, Sarah (1 July 2020). "Oxford offers best hope for Covid-19 vaccine this year, MPs told". Guardian News & Media Limited.
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