Anisopoikilocytosis

Anisopoikilocytosis
Slight to moderate anisopoikilocytosis in a case of polycythemia vera
SpecialtyHematology

Anisopoikilocytosis is a medical condition illustrated by a variance in size (anisocytosis) and shape (poikilocytosis) of a red blood cell. The underlying cause can be attributed to various anemias, most often; beta thalassemia major, a form of microcytic anemia.[1] In β thalassemia major the beta hemoglobin chain is completely absent, rendering an increase in fetal hemoglobin (HbF).[2]

References

  1. Alam, Kiran; Aziz, Mehar; Varshney, Manoranjan; Maheshwari, Veena; Basha, Mahfooz; Gaur, Kavita (2011-04-20). "Congenital dyserythropoietic anaemia type II: a rare entity". BMJ Case Reports. 2011: bcr0120113684. doi:10.1136/bcr.01.2011.3684. ISSN 1757-790X. PMC 3082060. PMID 22696622.
  2. Galanello, Renzo; Origa, Raffaella (2010-05-21). "Beta-thalassemia". Orphanet Journal of Rare Diseases. 5: 11. doi:10.1186/1750-1172-5-11. ISSN 1750-1172. PMC 2893117. PMID 20492708.


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