Anteroventral periventricular nucleus

Anteroventral periventricular nucleus
Identifiers
NeuroLex IDbirnlex_1401
Anatomical terms of neuroanatomy

The anteroventral periventricular nucleus (AVPV) is a small cluster of cells located in the preoptic area of hypothalamus of the brain that is abundant in nuclear hormone receptors in a sexually dimorphic manner, strongly implicated, in rat models, as being neonatally imprinted and subsequently controlling sex-typical physiology and behaviors.[1] This nucleus or cluster of cells is typically of bigger size in females than males, contrary to the sexually dimorphic nucleus (SDN) that is bigger in males.[2]

In rats and mice, the AVPV plus the periventricular nucleus make up the rostral periventricular region of the third ventricle (RP3V). This area is full of kisspeptin-expressing neurons and is involved in regulating GnRH neurons, and is responsible for the LH surge in female mice.

References

  1. ↑ Gore, A. (2008). "Developmental programming and endocrine disruptor effects on reproductive neuroendocrine systems". Frontiers in Neuroendocrinology. 29 (3): 358–374. doi:10.1016/j.yfrne.2008.02.002. PMC 2702520. PMID 18394690.
  2. ↑ LeVay, Simon (2011). Gay, Straight, and the Reason Why. New York: Oxford University Press. p. 52. ISBN 978-0-19-993158-3.


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