Chlorozotocin

Chlorozotocin
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-{[(2-Chloroethyl)(nitroso)carbamoyl]amino}-2-deoxy-D-glucose;
CAS Number	54749-90-5 ;
PubChem CID	451706;
ChemSpider	397854 ;
UNII	3053LTY75Z;
KEGG	C19170 ;
ChEMBL	ChEMBL2094020 ;
CompTox Dashboard (EPA)	DTXSID9020320 ;
Chemical and physical data
Formula	C9H16ClN3O7
Molar mass	313.69 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ClCCN(N=O)C(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO;
	InChI InChI=1S/C9H16ClN3O7/c10-1-2-13(12-20)9(19)11-5(3-14)7(17)8(18)6(16)4-15/h3,5-8,15-18H,1-2,4H2,(H,11,19)/t5-,6+,7+,8+/m0/s1 ; Key:MKQWTWSXVILIKJ-LXGUWJNJSA-N ;
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Chlorozotocin is a nitrosourea. It is used for cancer therapy.

The International Agency for Research on Cancer concluded it was "probably carcinogenic" in 1990^[1]

It is an analogue of streptozotocin.^[2]

References

↑ Humans, IARC Working Group on the Evaluation of Carcinogenic Risk to (1990). SUMMARY OF FINAL EVALUATIONS. International Agency for Research on Cancer.
↑ Wolfe MM (2006). Therapy of digestive disorders. Elsevier Health Sciences. p. 477. ISBN 978-1-4160-0317-5.

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