Comparison of neurofeedback software

Within the field of neurotechnology, Neurofeedback (NFB), also called neurotherapy, neurobiofeedback or EEG biofeedback (EEGBF) is a therapy technique which presents the user with real-time information about activity within their brain, as measured by electrical or blood-flow sensors on the scalp.

Brain activity is monitored and processed to provide feedback to the user in one of several ways, for example a video game rocket ship might accelerate when desired brainwaves are produced (positive feedback), or a film or music might pause when undesired brainwaves are produced (negative feedback). The user then uses this feedback to develop the brainwaves they wish to create and as a consequence, learn to gain more control over their brainwaves and therefore how they think and feel in every day situations. Neurofeedback has been used to help a range of conditions including ADHD and addictions.

General

Software Type Version Operating systems Developer License FDA cleared Supported Devices Under Active Development ~Price Bracket
BetterFly Neurofeedback Clinic 2.0; Home 2.0 Windows BetterFly Neurofeedback Proprietary Classification by device GENIUS, U-WIZ
BioEra Biofeedback: visual designer 2.0 Windows, Android PROATECH LLC Proprietary No (but basis of Cygnet and others) Pocket Neurobics,[1] BrainQuiry,[2] NeuroAmp,[3]

Neurobit Optima, Neurobit Optima+,

 Brainmaster,[4] QDS[2]
BioExplorer Neurofeedback 1.5 Windows Cyberevolution, Larry Janow Proprietary No "Intended for personal use..." Brainmaster,[4] BrainQuiry,[2] NeuroAmp,[3]

Neurobit Optima, Neurobit Optima+,

 J&J,[4] NeuroSky,[2]
 Pocket Neurobics,[1] QDS,[2] Telediagnostic Systems[4]
BioGraph Infiniti Neurofeedback/Biofeedback 6.1.0 Windows Thought Technology Ltd, Dr. Hal Myers Proprietary Yes Thought Technology[4]
BioTrace+ Neurofeedback, Biofeedback, QEEG 2015 Windows Mind Media B.V. Proprietary Medical class II NeXus by Mind Media[2] 4, 10 (MKII), 32
Brainathalon Game ? Java Amy Palke Open source No
BrainBay Neurofeedback: MIDI, particle display ? Windows Chris Veigl and Jeremy Wilkerson GPL No Neurobit Optima,

Neurobit Optima+ and more

BrainFeedback Pro Neurofeedback v12 Windows Deymed Diagnostic Proprietary Yes Deymed
BrainMaster Neurofeedback, Biofeedback, and QEEG; optional live z-scores (ANI or BrainDX), Live sLORETA Projector. various including BrainAvatar. Third-party SW includes: NeuroGuide, BioExplorer, BioERA, BrainPaint, SKIL, LENS, EEGer, BrainTrain, OpenVibe, EEGStudio Windows BrainMaster Technologies, Inc. Thomas F. Collura Proprietary; includes optional no-cost Application Programming Interfaces (API) FDA 510(k) clearance, ISO 13485 certification, and CE marking in Europe Brainmaster[4] 2E, 2EW, 2EB, Atlantis, Discovery, MINI-Q
BrainPaint Evidence Based Neurofeedback, with a validated[5] and replicated[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]
symptom based evaluation tool.
2.0
Includes BrainPrint, Alpha Theta, Brain-Heart Coherence, Couples Synchrony, Nonlinear, Slow Cortical Potential, Coherence training and all other frequency rewards and inhibits.
N/A BrainPaint, Inc. William C. Scott Proprietary FDA 510(k) clearance, ISO 13485 certification, and CE marking in Europe Brainmaster[4] 2E, 2EW, 2EB, Atlantis, Discovery
BWView Brainwave viewer 1.0.5 Linux, Windows Jim Peters GPL No
Cygnet Neurofeedback/Biofeedback


Neurofeedback: Frequency-band and SCP protocols according to Othmer,
particularly: SMR-Beta, ILF 1+2 channel, Synchrony, Alpha Theta.
with EEG NeuroAmp one or two channel protocols, with x23 or x39 optional 19 or 31 channels

Biofeedback: pIR HEG training with passive-infrared triple sensor pIRx3;
HRV, GSR, Temp with Combination Sensor.

2.0 Windows (any version) Developer: BEE Systems GmbH
Manufacturer: Corscience GmbH&CoKG
Distribution: BEE Medic Europe, BEE Medic EMEA, BEE Medic USA
Proprietary FDA class II, CE class IIa; including Cygnet Bio/Neurofeedback Software NeuroAmp[3] Bio/Neurofeedback device plus add-ons:
  • NeuroAmp x23 (23-channel digital EEG device)
  • NeuroAmp x39 (39-channel digital EEG device)
  • pIRx3 (3-channel passive infrared sensor)
  • tactile feedback
  • Combination Sensor (HRV, GSR, Temperature)
Dual Drive Pro Biofeedback GSR & Temp 3.0 Windows Somatic Vision Inc. Proprietary Unknown (not EEG)
eBioo Neurofeedback & Analysis

one-, two- and four channel training,
Amplitude-, relative Amplitude-, Coherence-,
Band-Ratio-, Asymmetry-inhibit-Training
and more ..

1.5 Windows Soft-dynamics, Geoffrey Arens Proprietary No – not stated or in FDA database Pocket Neurobics,[1] Neurobit Optima,[2] Brainmaster[4]
EEGDigiTrack Neurofeedback & Analysis 15.0.5.0 Windows ELMIKO Biosignals Ltd. Proprietary Safety class according to EN60601-1 - Class IIa, type BF Manufactured by ELMIKO Biosignals Ltd.:

EEG-2,

EEG-3,

EEG-4,

EEG-5,

ExG-32

Manufactured by Braintronics:

EEG-1166 Amplifier,

EEG-1142 Amplifier,

EEG-1042 Amplifier,

EEGer4 Neurofeedback & Analysis 4.3.0 Windows EEG Software LLC Proprietary FDA Class II J&J,[4] Telediagnostic Systems,[4] Phoenix Neuro Systems,[4]
Thought Technology,[4] Brainmaster,[4] Brainquiry,[2]
Pocket Neurobics,[1] external analog amplifiers
eProbe Neuro-Biofeedback Clinic 7.0; Home use 7.0 Windows ScienceBeam Proprietary CE, ISO 13485 eWave, eLab, , QEEG, EEG2-EEG128 channels

eWave, eLab, eWave+,

ElectricGuru Neurofeedback 0.4 Windows Rob Sacks Open source No
EventIDE Visual environment for designing behavioral experiments and mental games with real-time neurofeedback control and signal processing. 1.0 Windows Okazolab Ltd Proprietary No The majority of popular bio-amplifiers
LENSware Neurofeedback &Analysis 3 Windows OchsLabs Proprietary FDA Class II Exempt Ochslabs A200 amplifier
Mind WorkStation Neurofeedback, Biofeedback, and EEG-Driven Entrainment 1.3 Windows Transparent Corporation Proprietary No but can use Bioexplorer, Biograph, BioEra links See Bioexplorer, Biograph, BioEra
MindReflector Neurofeedback 1.1 Windows MindReflector Technologies, LLC Proprietary No NeuroSky[2]
Narbis Neurofeedback - Electrochromic Smart Glasses[22] 1.0 Android Narbis Proprietary "FDA Class II 510(k) Exempt

CE, IEC 62368-1:2014 (Second Edition), CFR 47 FCC Part 15 Subpart B EN 61000-3-2:2014 EN 61000-3-3:2013 EN 61326-1:2013"

Narbis Bluetooth Smart Glasses [23]
NeuroField Neurofeedback & Analysis 8.7.5 Windows NeuroField, Inc. Proprietary FDA Class II[24] X3000 Plus[25] and Q20 EEG[26][27]
neuromore Studio Customizable Biofeedback, protocol designing and automated therapy solution 1.2.0 Windows, Mac OS, Linux, Android, iOS neuromore Inc. Proprietary No
NeurOptimal Neurofeedback 3.0 Windows Valdeane W. Brown, Ph.D. Proprietary Unknown – not stated or in FDA database zAmp[2] from Zengar
NeuroRT Suite

Koala

Modulo

Real-time Processing, Self Neuromodulation, Bio/Neurofeedback 2.2 Windows, Linux, Android Mensia Technologies Proprietary Medical device CE class IIa
  • ANT: All devices
  • Biosemi: ActiveTwo Mk I and ActiveTwo Mk II
  • Brainmaster: Atlantis and Discovery 24
  • Brain Products: ActiCHamp, BrainAmp series, QuickAmp and vAMP
  • Cognionics: Cognionics64
  • EGI: NetAmps 300
  • Emotiv: EPOC
  • g.Tec: gMobilab+ and gUSBamp
  • MindMedia: NeXus32, NeXus10
  • Mitsar: EEG 202;
  • NeuroElectrics: Enobio
  • OpenEEG: ModularEEG
  • Shimmer
  • TMSi: Porti, Refa, MOBITA, MOBI, MOBI mini
  • Wearable Sensing: DSI24 and DSI6
NeuroServer Raw EEG to TCP/IP + EDF converter 0.7.4 Linux, Windows [Rudi Cilibrasi] GPL No
OpenViBE BCI, Visual Designer, Analysis, Neurofeedback 0.18 Linux, Windows INRIA AGPL-3 No List of compatible systems
SmartMind Neurofeedback v2010 Windows BrainTrain, Inc. Proprietary Unknown – not stated or in FDA database Smartmind,[2] Brainmaster,[4] Thought Technology,[4] J&J,[4]
Pocket Neurobics,[1] NeuroSky[2]
Myndlift Neurofeedback: Single-active channel, amplitude training - home-based remote training  ? Android, iOS Myndlift LTD Proprietary No Muse
Vilistus Neurofeedback/Biofeedback v5.2.5 Windows Stephen Clark Proprietary No Vilistus
  1. 1 2 3 4 5 Multiple NON-FDA-cleared devices
  2. 1 2 3 4 5 6 7 8 9 10 11 12 Status Unknown
  3. 1 2 3 FDA-cleared device
  4. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Multiple FDA-cleared devices
  5. Scott, William C.; Kaiser, David; Othmer, Siegfried; Sideroff, Stephen I. (7 July 2009). "Effects of an EEG Biofeedback Protocol on a Mixed Substance Abusing Population". The American Journal of Drug and Alcohol Abuse. 31 (3): 455–69. doi:10.1081/ADA-200056807. PMID 16161729. S2CID 6931394.
  6. Keith, Julian R.; Rapgay, Lobsang; Theodore, Don; Schwartz, Jeffrey M.; Ross, Jae L. (March 2015). "An assessment of an automated EEG biofeedback system for attention deficits in a substance use disorders residential treatment setting". Psychology of Addictive Behaviors. 29 (1): 17–25. doi:10.1037/adb0000016. PMC 5495545. PMID 25180558.
  7. Dehghani-Arani, Fateme; Rostami, Reza; Nadali, Hosein (20 April 2013). "Neurofeedback Training for Opiate Addiction: Improvement of Mental Health and Craving". Applied Psychophysiology and Biofeedback. 38 (2): 133–141. doi:10.1007/s10484-013-9218-5. PMC 3650238. PMID 23605225.
  8. Arani, Fateme Dehghani; Rostami, Reza; Nostratabadi, Masoud (July 2010). "Effectiveness of Neurofeedback Training as a Treatment for Opioid-Dependent Patients". Clinical EEG and Neuroscience. 41 (3): 170–177. doi:10.1177/155005941004100313. PMID 20722354. S2CID 35834162.
  9. Egner, T; Gruzelier, JH (January 2004). "EEG biofeedback of low beta band components: frequency-specific effects on variables of attention and event-related brain potentials". Clinical Neurophysiology. 115 (1): 131–9. doi:10.1016/S1388-2457(03)00353-5. PMID 14706480. S2CID 5855076.
  10. Dalkner, Nina; Unterrainer, Human F.; Wood, Guilherme; Skliris, Dimitris; Holasek, Sandra J.; Gruzelier, John H.; Neuper, Christa (26 September 2017). "Short-term Beneficial Effects of 12 Sessions of Neurofeedback on Avoidant Personality Accentuation in the Treatment of Alcohol Use Disorder". Frontiers in Psychology. 8: 1688. doi:10.3389/fpsyg.2017.01688. PMC 5622970. PMID 29018397.
  11. Lackner, Nina; Unterrainer, Human F.; Skliris, Dimitris; Wood, Guilherme; Wallner-Liebmann, Sandra J.; Neuper, Christa; Gruzelier, John H. (27 September 2015). "The Effectiveness of Visual Short-Time Neurofeedback on Brain Activity and Clinical Characteristics in Alcohol Use Disorders". Clinical EEG and Neuroscience. 47 (3): 188–195. doi:10.1177/1550059415605686. PMID 26415612. S2CID 34971632.
  12. Horrell, Timothy; El-Baz, Ayman; Baruth, Joshua; Tasman, Allan; Sokhadze, Guela; Stewart, Christopher; Sokhadze, Estate (16 August 2010). "Neurofeedback Effects on Evoked and Induced EEG Gamma Band Reactivity to Drug-Related Cues in Cocaine Addiction". Journal of Neurotherapy. 14 (3): 195–216. doi:10.1080/10874208.2010.501498. PMC 2957125. PMID 20976131.
  13. Unterrainer, Human F.; Lewis, Andrew J.; Gruzelier, John H. (2013). "EEG-Neurofeedback in psychodynamic treatment of substance dependence". Frontiers in Psychology. 4: 692. doi:10.3389/fpsyg.2013.00692. PMC 3787602. PMID 24098295.
  14. Fattahi, Samineh; Naderi, Farah; Asgari, Parviz; Ahadi, Hassan (27 June 2017). "Neuro-Feedback Training For Overweight Women: Improvement of Food Craving And Mental Health". NeuroQuantology. 15 (2). doi:10.14704/nq.2017.15.2.1067.
  15. Rostami, R.; Dehghani-Arani, F. (19 April 2015). "Neurofeedback Training as a New Method in Treatment of Crystal Methamphetamine Dependent Patients: A Preliminary Study". Applied Psychophysiology and Biofeedback. 40 (3): 151–161. doi:10.1007/s10484-015-9281-1. PMID 25894106. S2CID 42223626.
  16. "Quantitative Electroencephalography-Guided Versus Scott/Peniston Neurofeedback With Substance Use Disorder Outpatients" (PDF). www.aapb.org/files/publications/biofeedback/2007/biof_winter_pilot_study.pdf.
  17. Nooner, Kate B.; Leaberry, Kirsten D.; Keith, Julian R.; Ogle, Richard L. (17 May 2016). "Clinic Outcome Assessment of a Brief Course Neurofeedback for Childhood ADHD Symptoms". The Journal of Behavioral Health Services & Research. 44 (3): 506–514. doi:10.1007/s11414-016-9511-1. PMID 27189699. S2CID 7386924.
  18. Ros, T.; Frewen, P.; Théberge, J.; Michela, A.; Kluetsch, R.; Mueller, A.; Candrian, G.; Jetly, R.; Vuilleumier, P.; Lanius, R. A. (12 September 2016). "Neurofeedback Tunes Scale-Free Dynamics in Spontaneous Brain Activity". Cerebral Cortex. 27 (10): 4911–4922. arXiv:1512.09133. doi:10.1093/cercor/bhw285. PMID 27620975.
  19. Nicholson, Andrew A.; Ros, Tomas; Frewen, Paul A.; Densmore, Maria; Théberge, Jean; Kluetsch, Rosemarie C.; Jetly, Rakesh; Lanius, Ruth A. (February 2016). "Alpha oscillation neurofeedback modulates amygdala complex connectivity and arousal in posttraumatic stress disorder". NeuroImage: Clinical. 12: 506–516. doi:10.1016/j.nicl.2016.07.006. PMC 5030332. PMID 27672554.
  20. Kluetsch, R. C.; Ros, T.; Théberge, J.; Frewen, P. A.; Calhoun, V. D.; Schmahl, C.; Jetly, R.; Lanius, R. A. (August 2014). "Plastic modulation of PTSD resting-state networks and subjective wellbeing by EEG neurofeedback". Acta Psychiatrica Scandinavica. 130 (2): 123–136. doi:10.1111/acps.12229. PMC 4442612. PMID 24266644.
  21. Mazur, L. M.; Campbell, A.; Comitz, E.; Planting, D.; Lowen, S.; Mosaly, P. R.; Belger, A.; Chera, B. S.; Marks, L. B. (2017). "Positive effects of neurofeedback intervention on radiation oncology physicians' workload during go/no-go performance test". Le Travail Humain. 80 (1): 113–32. doi:10.3917/th.801.0113.
  22. "Neurofeedback - Electrochromic Smart Glasses".
  23. "Narbis Bluetooth Smart Glasses".
  24. "Establishment Registration & Device Listing". www.accessdata.fda.gov. Retrieved 2015-09-22.
  25. "X3000 Plus – NeuroField – The Energetic Wave of the Future". Retrieved 2015-09-22.
  26. "Q20 EEG – NeuroField – The Energetic Wave of the Future". Archived from the original on 2015-09-10. Retrieved 2015-09-22.
  27. "X3000 Plus and Q20 EEG – NeuroField – The Energetic Wave of the Future". Archived from the original on 2015-08-11. Retrieved 2015-09-22.

See also

  • Neurofeedback
  • Brainwave synchronization
  • Comparison of brainwave entrainment software
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