Effective renal plasma flow
| Parameter | Value |
|---|---|
| renal blood flow | RBF = 1000 mL/min |
| hematocrit | HCT = 40% |
| glomerular filtration rate | GFR = 120 mL/min |
| renal plasma flow | RPF = 600 mL/min |
| filtration fraction | FF = 20% |
| urine flow rate | V = 1 mL/min |
| Sodium | Inulin | Creatinine | PAH |
|---|---|---|---|
| SNa = 150 mEq/L | SIn = 1 mg/mL | SCr = 0.01 mg/mL | SPAH = |
| UNa = 710 mEq/L | UIn = 150 mg/mL | UCr = 1.25 mg/mL | UPAH = |
| CNa = 5 mL/min | CIn = 150 mL/min | CCr = 125 mL/min | CPAH = 420 mL/min |
| ER = 90% | |||
| ERPF = 540 mL/min |
Effective renal plasma flow (eRPF) is a measure used in renal physiology[1] to calculate renal plasma flow (RPF) and hence estimate renal function. The eRPF can be calculated with
where extraction ratio is the ratio of compound entering the kidney that is excreted into the final urine.[2]
When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), eRPF approximates RPF. Therefore, PAH clearance can be used to estimate RPF.[3]
References
- ↑ "Hubio562: Clearance Lab Answers". Archived from the original on September 12, 2006. Retrieved 2009-04-29.
- ↑ Barrett, Kim E.; Brooks, Heddwen L.; Boitano, Scott; Barman, Susan M. (2010). Ganong's Review of Medical Physiology (23rd ed.). McGraw-Hill Medical. pp. 643–644. ISBN 978-0-07-160568-7. OCLC 430823856.
- ↑ Costanzo, Linda (2012). Physiology Cases and Problems. Lippincott Williams & Wilkins. p. 165. ISBN 9781451120615. Retrieved 1 November 2018.
External links
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