Erythromer

ErythroMer is a red blood substitute in development funded by the National Institutes of Health and U.S. Department of Defense.[1] Similar to other HBOCs, the product is stable for several months even when freeze-dried, and can be reconstituted from its lyophilized state in emergency situations. This opens up the possibility of eventual stockpiling of ErythoMer making it easier to supply blood in large amounts to those who need it.[2]

The development of this technology was done at Washington University at St. Louis and UIUC.[3] Trials have been successful in rats, mice, and rabbits, and human trials are planned.[4]

ErythroMer is a reddish blood powder composed from hemoglobin from humans. By coating it with a synthetic polymer, it is able to sense pH changes, allowing for oxygen pick up in areas where the pH levels are high, and disposal where the levels are low.[2]

References

  1. ↑ "Grants and Contracts | Anesthesia Faculty Scholarship Newsletter | Perelman School of Medicine at the University of Pennsylvania". Med.upenn.edu. 2016-09-30. Archived from the original on 2016-12-02. Retrieved 2016-12-03.
  2. 1 2 "The long quest to create artificial blood may soon be over". NBC News. Retrieved 2017-01-25.
  3. ↑ "ErythroMer Blood Substitute | Washington University in St. Louis". Otm.wustl.edu. Retrieved 2016-12-03.
  4. ↑ "1027 Erythromer (EM), a Nanoscale Bio-Synthetic Artificial Red Cell: Proof of Concept and In Vivo Efficacy Results". Ash.confex.com. Retrieved 2016-12-03.
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