Nevus comedonicus
| Nevus comedonicus syndrome | |
|---|---|
 | |
| a) Nevus along Blaschko's lines over the chest, b) over leg | |
 | |
| Specialty | Dermatology |
| Symptoms | Clusters of small bumps filled with keratinous plugs[1] |
| Usual onset | Birth to age 15 years[1] |
| Causes | Gene mutation[1] |
| Treatment | Pore-cleansing strips, squeezing the comedones, applying tretinoin, CO2 laser, surgery[1] |
| Frequency | Rare, males=females[2] |
Nevus comedonicus, also known as a comedo nevus, is characterized by a cluster of small bumps containing keratinous plugs resembling comedones.[1][2] It tends to occur more frequently on the face and neck and may present in a linear, Blaschkoid or segmental pattern.[3] It generally appears any time between birth and age 15 years, and is usually unilateral.[1]
It is caused by mutations during development of the unborn baby.[1] If nevus comedonicus occurs with eye, bone and nerve abnormalities, it is called Nevus comedonicus syndrome.[3]
Treatment is with pore-cleansing strips, squeezing the comedones, applying tretinoin and CO2 laser.[1] Cutting it out may be an option if the disease affects a small area.[1]
It is rare, males and females are affected equally, and around half present at birth.[2]
Signs and symptoms
Nevus comedonicus: clusters and Blaschkoid distribution
Nevus comedonicus: Linear pattern
Diagnosis
See also
References
- 1 2 3 4 5 6 7 8 9 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "29. Epidermal nevi, neoplasms, and cysts". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 637. ISBN 978-0-323-54753-6. Archived from the original on 2022-04-19. Retrieved 2022-04-18.
- 1 2 3 "Comedo naevus (comedone nevus): Causes, Images, and More - DermNet". dermnetnz.org. Archived from the original on 2022-04-07. Retrieved 2022-04-18.
- 1 2 Zhu, Yong-Hang (2018). "27. Tumours of the skin". In Zhu, Wen-Yuan; Tan, Cheng; Zhang, Ru-zhi (eds.). Atlas of Skin Disorders: Challenging Presentations of Common to Rare Conditions. Springer. p. 480. ISBN 978-981-10-8036-4. Archived from the original on 2022-04-20. Retrieved 2022-04-18.