Pharmacogene Variation Consortium
 | |
|---|---|
| Content | |
| Description | The PharmVar Consortium |
| Data types captured | Pharmacogenomics and Pharmacogenetics |
| Organisms | Human |
| Contact | |
| Research center | Children's Mercy Hospital |
| Primary citation | PMID 29134625 |
| Release date | 2017 |
| Access | |
| Website | www |
| Download URL | www |
| Web service URL | www |
| Miscellaneous | |
| Curation policy | Yes |
Pharmacogene Variation Consortium (abbreviated as PhamVar) is an international group of experts that maintains a systematic nomenclature system for allelic variations of genes that affect the metabolism of drugs.[1][2]
The database is focused on cytochrome P450 enzymes, but is being expanded into other classes of enzymes. The original nomenclature was maintained by the Human CYP Allele Nomenclature Database. However PhamVar took over this function in 2017.[3]
See also
References
- ↑ Gaedigk A, Ingelman-Sundberg M, Miller NA, Leeder JS, Whirl-Carrillo M, Klein TE (March 2018). "The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database". Clinical Pharmacology and Therapeutics. 103 (3): 399–401. doi:10.1002/cpt.910. PMC 5836850. PMID 29134625.
- ↑ Gaedigk A, Sangkuhl K, Whirl-Carrillo M, Twist GP, Klein TE, Miller NA (January 2019). "The Evolution of PharmVar". Clinical Pharmacology and Therapeutics. 105 (1): 29–32. doi:10.1002/cpt.1275. PMC 6312487. PMID 30536702.
- ↑ Tornio A, Backman JT (2018). "Cytochrome P450 in Pharmacogenetics: An Update". Pharmacogenetics. Advances in Pharmacology. Vol. 83. San Diego, Calif. pp. 3–32. doi:10.1016/bs.apha.2018.04.007. hdl:10138/300396. ISBN 9780128133811. PMID 29801580.
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