Prostate hypoplasia

Prostate hypoplasia is the congenital abnormality of a small (or absent) prostate gland. Often associated with other abnormalities of the urogenital system. Often due to abnormality in mesenchymal cells and associated with prune belly syndrome.[1] Observed in 5α-reductase 2 deficiency in which impaired 5α-dihydrotestosterone (DHT) synthesis impairs prostate development which is DHT dependent.[2]

References

  1. ↑ Hricak, Hedvig (1991). MRI of the Pelvis: A Text Atlas. Taylor & Francis. p. 252. ISBN 978-0-8385-6527-8.
  2. ↑ Mendonca, Berenice B.; Batista, Rafael Loch; Domenice, Sorahia; Costa, Elaine M.F.; Arnhold, Ivo J.P.; Russell, David W.; Wilson, Jean D. (October 2016). "Steroid 5α-reductase 2 deficiency". The Journal of Steroid Biochemistry and Molecular Biology. 163: 206–211. doi:10.1016/j.jsbmb.2016.05.020. PMID 27224879. S2CID 26748233.


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