Pyrrocaine

Pyrrocaine
Names
Preferred IUPAC name
N-(2,6-Dimethylphenyl)-2-(pyrrolidin-1-yl)acetamide
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
EC Number
  • 218-642-7
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C14H20N2O/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7H,3-4,8-10H2,1-2H3,(H,15,17)
    Key: OYCGKECKIVYHTN-UHFFFAOYSA-N
SMILES
  • Cc1cccc(c1NC(=O)CN2CCCC2)C
Properties
Chemical formula
 C14H20N2O
Molar mass 232.327
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pyrrocaine is a local anesthetic drug. The cogency of pyrrocaine is equivalent to lidocaine in blocking the motor nerve and sensory. Pyrrocaine was proven to be somewhat harmless compared to lidocaine. No signs of methemoglobinemia was found while observing. It was considered unsafe for acute porphyria treatment. No evidence is found that it is profitly used now.[1]

History

In the 1960s it was most of the time used as a nerve blocker dental anesthetic and dentists recommended it due to its fast commencement.[1]

Adverse effects

Pyrrocane has very similar side effects on blood pressure and heart rate compared to lidocaine.[2]

See also

References

  1. 1 2 "NCATS Inxight: Drugs". drugs.ncats.io. Retrieved 2018-08-07.
  2. ↑ Annals of Dentistry. New York Academy of Dentistry. 1983.
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