Spinetoram

Spinetoram
Clinical data
Trade namesCheristin
ATCvet code
Identifiers
IUPAC name
  • (2R,5R,9R,10S,14R,15S,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-7-[(2R,3R,4R,5S,6S)-4-ethoxy-3,5-dimethoxy-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-20-oxatetracyclo[10.10.0.02,10.05,9]docos-11-ene-13,21-dione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.211.310
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Chemical and physical data
FormulaC42H69NO10
Molar mass748.011 g·mol−1
3D model (JSmol)
SMILES
  • CCC1CCCC(C(C(=O)C2=CC3C(C2CC(=O)O1)CCC4C3CC(C4)OC5C(C(C(C(O5)C)OC)OCC)OC)C)OC6CCC(C(O6)C)N(C)C
InChI
  • InChI=InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1 checkY
  • Key:GOENIMGKWNZVDA-OAMCMWGQSA-N

Spinetoram (marketed as Cheristin in its topical veterinary dosage-form) is an insecticidal mixture of two active neurotoxic constituents of Saccharopolyspora spinosa.[1] It is used to control pest insects in stored grain[2] and on domestic cats.[3]

See also

References

  1. ↑ Bacci L, Lupi D, Savoldelli S, Rossaro B (2016-04-28). "A review of Spinosyns, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests". Journal of Entomological and Acarological Research. 48 (1): 40. doi:10.4081/jear.2016.5653. ISSN 2279-7084.
  2. ↑ Vassilakos TN, Athanassiou CG, Tsiropoulos NG (2015). "Influence of grain type on the efficacy of spinetoram for the control of Rhyzopertha dominica, Sitophilus granarius and Sitophilus oryzae". Journal of Stored Products Research. 64: 1–7. doi:10.1016/j.jspr.2015.02.002.
  3. ↑ Paarlberg T, Winkle J, Rumschlag AJ, Young LM, Ryan WG, Snyder DE (February 2017). "®) for cats". Parasites & Vectors. 10 (1): 59. doi:10.1186/s13071-017-1996-9. PMC 5288883. PMID 28148275.
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