Nifurtoinol

Nifurtoinol
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	J01XE02 (WHO) ;
Pharmacokinetic data
Excretion	Renal (40–50% within the first 12 hours)
Identifiers
	IUPAC name 3-(hydroxymethyl)-1-{[(1E)-(5-nitro-2-furyl); methylene]amino}imidazolidine-2,4-dione;
CAS Number	1088-92-2 ;
PubChem CID	9571062;
ChemSpider	7845528 ;
UNII	980688H13O;
KEGG	D07243 ;
ChEBI	CHEBI:88255 ;
CompTox Dashboard (EPA)	DTXSID30148747 ;
ECHA InfoCard	100.012.842
Chemical and physical data
Formula	C9H8N4O6
Molar mass	268.185 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C(=O)N(C(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-])CO;
	InChI InChI=1S/C9H8N4O6/c14-5-11-7(15)4-12(9(11)16)10-3-6-1-2-8(19-6)13(17)18/h1-3,14H,4-5H2/b10-3+ ; Key:UIDWQGRXEVDFCA-XCVCLJGOSA-N ;
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Nifurtoinol (rINN, trade name Urfadyn) is a nitrofuran-derivative antibiotic used in the treatment of urinary tract infections.

It is also known as "hydroxymethylnitrofurantoin".^[1]

References

↑ Stricker BH, Blok AP, Claas FH, Van Parys GE, Desmet VJ (1988). "Hepatic injury associated with the use of nitrofurans: a clinicopathological study of 52 reported cases". Hepatology. 8 (3): 599–606. doi:10.1002/hep.1840080327. PMID 3371877.

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