(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
The enzyme (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) catalyzes the chemical reaction
- (1-hydroxycyclohexan-1-yl)acetyl-CoA acetyl-CoA + cyclohexanone
| (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.3.35 | ||||||||
| CAS no. | 71343-09-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.
References
- Ougham HJ, Trudgill PW (June 1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". Journal of Bacteriology. 150 (3): 1172–82. PMC 216338. PMID 7076617.
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