(2R)-3-sulfolactate dehydrogenase (NADP+)
(2R)-3-sulfolactate dehydrogenase (NADP+) (EC 1.1.1.338, (R)-sulfolactate:NADP+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenase, ComC) is an enzyme with systematic name (2R)-3-sulfolactate:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- (2R)-3-sulfolactate + NADP+ 3-sulfopyruvate + NADPH + H+
| (2R)-3-sulfolactate dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.338 | ||||||||
| CAS no. | 81210-65-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+.
References
- Denger K, Cook AM (March 2010). "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase" (PDF). Microbiology. 156 (Pt 3): 967–74. doi:10.1099/mic.0.034736-0. PMID 20007648.
External links
- (2R)-3-sulfolactate+dehydrogenase+(NADP+) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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