(Pyruvate, phosphate dikinase)-phosphate phosphotransferase
(Pyruvate, phosphate dikinase)-phosphate phosphotransferase (EC 2.7.4.27, PPDK regulatory protein, pyruvate, phosphate dikinase regulatory protein, bifunctional dikinase regulatory protein, PDRP1 (gene)) is an enzyme with systematic name (pyruvate, phosphate dikinase) phosphate:phosphate phosphotransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- [pyruvate, phosphate dikinase] phosphate + phosphate [pyruvate, phosphate dikinase] + diphosphate
| (Pyruvate, phosphate dikinase)-phosphate phosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.4.27 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme from the plants maize and arabidopsis is bifunctional and also catalyses the phosphorylation of pyruvate (EC 2.7.11.32).
References
- Burnell JN, Hatch MD (May 1984). "Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase". Archives of Biochemistry and Biophysics. 231 (1): 175–82. doi:10.1016/0003-9861(84)90375-8. PMID 6326674.
- Burnell JN, Hatch MD (March 1985). "Regulation of C4 photosynthesis: purification and properties of the protein catalyzing ADP-mediated inactivation and Pi-mediated activation of pyruvate,Pi dikinase". Archives of Biochemistry and Biophysics. 237 (2): 490–503. doi:10.1016/0003-9861(85)90302-9. PMID 2983615.
- Chastain CJ, Botschner M, Harrington GE, Thompson BJ, Mills SE, Sarath G, Chollet R (March 2000). "Further analysis of maize C(4) pyruvate,orthophosphate dikinase phosphorylation by its bifunctional regulatory protein using selective substitutions of the regulatory Thr-456 and catalytic His-458 residues". Archives of Biochemistry and Biophysics. 375 (1): 165–70. doi:10.1006/abbi.1999.1651. PMID 10683263.
- Burnell JN, Chastain CJ (June 2006). "Cloning and expression of maize-leaf pyruvate, Pi dikinase regulatory protein gene". Biochemical and Biophysical Research Communications. 345 (2): 675–80. doi:10.1016/j.bbrc.2006.04.150. PMID 16696949.
- Chastain CJ, Xu W, Parsley K, Sarath G, Hibberd JM, Chollet R (March 2008). "The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure". The Plant Journal. 53 (5): 854–63. doi:10.1111/j.1365-313x.2007.03366.x. PMID 17996018.
External links
- (pyruvate,+phosphate+dikinase)-phosphate+phosphotransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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