(deoxy)adenylate kinase
In enzymology, a (deoxy)adenylate kinase (EC 2.7.4.11) is an enzyme that catalyzes the chemical reaction
- ATP + dAMP ADP + dADP
(deoxy)adenylate kinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.4.11 | ||||||||
CAS no. | 37278-19-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are ATP and dAMP, whereas its two products are ADP and dADP.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)AMP phosphotransferase. This enzyme participates in purine metabolism.
References
- Griffith TJ, Helleiner CW (1965). "The partial purification of deoxynucleoside monophosphate kinases from L cells". Biochim. Biophys. Acta. 108 (1): 114–24. doi:10.1016/0005-2787(65)90113-9. PMID 5862227.
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