1,6-alpha-L-fucosidase
The enzyme 1,6-α-L-fucosidase (EC 3.2.1.127) catalyses the following chemical reaction
- Hydrolysis of 1,6-linkages between α-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin
| 1,6-α-L-Fucosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.127 | ||||||||
| CAS no. | 102925-35-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase. It is also called α-L-fucosidase.
References
- Yazawa S, Madiyalakan R, Chawda RP, Matta KL (1986). "α-L-fucosidase from Aspergillus niger: demonstration of a novel α-L-(1→6)-fucosidase acting on glycopeptides". Biochem. Biophys. Res. Commun. 136 (2): 563–9. doi:10.1016/0006-291X(86)90477-8. PMID 2423086.
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