2-dehydro-3-deoxy-L-pentonate aldolase

The enzyme 2-dehydro-3-deoxy-L-pentonate aldolase (EC 4.1.2.18) catalyzes the chemical reaction

2-dehydro-3-deoxy-L-pentonate pyruvate + glycolaldehyde
2-dehydro-3-deoxy-L-pentonate aldolase
Identifiers
EC no.4.1.2.18
CAS no.9076-49-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-L-pentonate aldolase, 2-keto-3-deoxy-L-arabonate aldolase, 2-keto-3-deoxy-D-xylonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.

References

    • Dahms AS, Anderson RL (1969). "2-keto-3-deoxyl-L-arabonate aldolase and its role in a new pathway of L-arabinose degradation". Biochem. Biophys. Res. Commun. 36 (5): 809–14. doi:10.1016/0006-291X(69)90681-0. PMID 5808295.


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