2-Phospho-L-lactate guanylyltransferase

2-Phospho-L-lactate guanylyltransferase (EC 2.7.7.68, CofC, MJ0887) is an enzyme with systematic name GTP:2-phospho-L-lactate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

(2S)-2-phospholactate + GTP (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate
2-Phospho-L-lactate guanylyltransferase
Identifiers
EC no.2.7.7.68
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is involved in the biosynthesis of coenzyme F420.

References

  1. Grochowski LL, Xu H, White RH (March 2008). "Identification and characterization of the 2-phospho-L-lactate guanylyltransferase involved in coenzyme F420 biosynthesis". Biochemistry. 47 (9): 3033–7. doi:10.1021/bi702475t. PMID 18260642.
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