2008 American League Championship Series

Tampa Bay won the series, 4–3.

Boston won a pitcher's duel on a sacrifice fly by Jed Lowrie in the fifth off of James Shields and an RBI double by Kevin Youkilis in the eighth off of J. P. Howell with the run charged to Shields. Starter Daisuke Matsuzaka held the Rays hitless until Carl Crawford singled to lead off the seventh inning. He allowed four singles and five walks in seven innings while striking out nine. Jonathan Papelbon pitched a perfect ninth for his fourth career ALCS save.

The Rays won a hard-hitting, marathon game that lasted 5 hours and 27 minutes,[13] and featured seven home runs, which broke the ALCS record and tied the all-time LCS record.[14] Starters Scott Kazmir and Josh Beckett were both ineffective, giving up six of those home runs and lasting under five innings.

In the top of the first, David Ortiz walked and Kevin Youkilis singled with two outs before both scored on Jason Bay's double, but in the bottom of the inning, Carlos Pena doubled with two outs before Evan Longoria's home run tied the game. Dustin Pedroia's leadoff home run in the third put the Red Sox up 3−2, but in the bottom of the inning, B. J. Upton's one-out home run tied the game again, then Longoria doubled with two outs before scoring on Carl Crawford's single to put the Rays up 4–3. Cliff Floyd's leadoff home run in the fourth extended the Rays' lead to 5–3, but home runs by Pedroia and Youkilis in the fifth tied the game. Grant Balfour relieved Kazmir and allowed a home run to Bay to put the Red Sox up 6–5. In the bottom of the inning, Upton walked without out, stole second and scored on Pena's single to tie the game. Longoria's RBI double then put the Rays up 7–6. Javier Lopez relieved Beckett and allowed an RBI single to Crawford. Bay's single in the seventh off of Chad Bradford scored Pedroia, who walked off of J. P. Howell with one out earlier that inning. A wild pitch by Dan Wheeler in the eighth allowed Pedroia, who singled to lead off the inning off of Bradford, to score and tie the game, forcing extra innings. In the bottom of the 11th, Mike Timlin walked three to load the bases before a sacrifice fly by Upton allowed Fernando Perez to score the winning run. The Rays' 2007 #1 draft pick, David Price, was credited with the win.

The Rays hit Boston ace Jon Lester and reliever Paul Byrd hard in Game 3, moving ahead two games to one. The Rays scored their first run in the second on Dioner Navarro's RBI groundout with runners on second and third. Next inning, B. J. Upton hit a towering three-run homer over the Green Monster to make it 4–0. Evan Longoria followed with a home run later in the inning to make it 5–0. Tampa Bay starter Matt Garza pitched brilliantly against the Red Sox lineup. The 3–4–5 hitters went 0–9 against him and the Red Sox's only run came in the seventh on Jacoby Ellsbury's sacrifice fly off of J. P. Howell that scored Jason Varitek, who walked off of Garza to lead off the inning. In the eighth, New England native Rocco Baldelli hit a three-run homer of his own, also over the Green Monster, off of Byrd to seal the win. Carlos Peña homered in the ninth, also off of Byrd to extend his postseason success.

The Rays routed the defending World Champions for the second straight night with a 13–4 win in Boston. Carlos Peña got it going in the first with a two-run homer off starter Tim Wakefield. Evan Longoria followed it up with his third homer of the series and fifth in the playoffs. Willy Aybar hit his first home run of the postseason in the third when he sent one over the Green Monster for a two-run homer. Kevin Cash's leadoff home run in the third off of Rays starter Andy Sonnanstine put the Red Sox on the board. In the fifth, Carl Crawford doubled with one out in the fifth off of Justin Masterson and scored on Aybar's single. Next inning, Jason Bartlett tripled with one out off of Manny Delcarmen.

After Akinori Iwamura walked, B. J. Upton's RBI single made it 7–1 Rays. Delcarmen walked two to load the bases and force in another run before being relieved by Javier Lopez, who allowed back-to-back RBI singles to Crawford and Aybar, then an RBI groundout to Navarro. In the bottom of the inning, David Ortiz hit a leadoff triple and scored on Kevin Youkilis's groundout. In the eighth, Mike Timlin walked Pena to lead off the inning, then allowed an RBI triple to Crawford and RBI single to Aybar. In the bottom of the inning, Jed Lowrie hit a leadoff single, moved to second on a groundout and scored on Dustin Pedroia's single. Trever Miller relieved Sonnastine and allowed a two-out RBI double to Youkilis. Edwin Jackson pitched a scoreless ninth as the Rays were one win away from the World Series. Carl Crawford went 5-for-5 with two stolen bases in the game.

Tampa Bay jumped out to an early lead when B. J. Upton hit a two-run home run with no one out in the first inning. Carlos Peña and Evan Longoria increased the lead to 5–0 with back-to-back home runs in the third, the former a two-run shot. With his home run, Longoria tied Carlos Beltrán's record for consecutive postseason games with a home run. Daisuke Matsuzaka allowed no more runs after that through six innings, but Boston was unable to score against Scott Kazmir. In the top of the seventh, Jonathan Papelbon came on after Manny Delcarmen walked the only two batters he faced. The inherited runners scored on an Upton double, making it 7–0.

In the bottom of the seventh, with two outs and runners on first and third, Dustin Pedroia hit an RBI single off Grant Balfour to finally get the Red Sox on the board. The next batter, David Ortiz, hit a three-run home run to right field, ending a postseason home run drought of 61 at-bats. In the eighth inning, J. D. Drew hit a two-run homer to right field off Dan Wheeler. Later, Coco Crisp hit an RBI single to right field to score Mark Kotsay from second to tie the game. In the ninth inning, after J. P. Howell retired the first two Boston batters, Kevin Youkilis hit a ground ball to third base. Longoria scooped the ball, but his throw was off, and bounced into the stands, allowing Youkilis to reach second. After an intentional walk to Jason Bay, Drew hit a single over the head of right fielder Gabe Gross to win the game.

The comeback of the Red Sox from a seven-run deficit is the second-biggest in postseason history, the largest since Game 4 of the 1929 World Series,[15] and the largest ever for a team on the brink of elimination.

All Star Kevin Youkilis

Josh Beckett pitched five innings and allowed two solo home runs, to B. J. Upton in the first and Jason Bartlett in the fifth, to record the win. Boston scored on home runs from Kevin Youkilis in the second and Jason Varitek (his first series hit) in the sixth, a Youkilis groundout in the third, and a single by David Ortiz after Bartlett's throwing error extended the sixth inning.

Umpire Derryl Cousins was struck by a foul ball from Varitek in the second inning, leaving the game with a bruised collarbone after the third. The game was delayed for 15 minutes while Cousins was X-rayed by Rays trainer Ron Porterfield; the game resumed with a five-man umpiring crew.

TBS television missed most of the game's first inning, with viewers getting a rerun of The Steve Harvey Show instead. The network picked up the game just prior to the last out in the bottom of the first, with announcer Chip Caray apologizing to viewers for "technical difficulties". TBS acknowledged there was a problem with one of their routers used in the broadcast transmission of the relay of the telecast from Atlanta.[16][17]

When facing elimination, Terry Francona's Red Sox won nine of ten postseason games.[18]

The Rays shook off the ghosts of Red Sox past to win their first American League pennant, winning a tight game 3–1. Dustin Pedroia got the Red Sox off to a good start with a one-out homer in the first off Matt Garza, but Garza settled in and delivered an MVP performance. Tampa Bay tied the game in the fourth with an Evan Longoria RBI double, then went ahead in the fifth on an RBI single by Rocco Baldelli. In the seventh, Willy Aybar added insurance with a home run to lead off. In the eighth, David Price, who made his major league debut a little over a month before came on to pitch to J. D. Drew with the bases loaded and struck him out on a checked swing. In the ninth, Price recorded his first Major League save by getting Jed Lowrie to ground into a force play to Akinori Iwamura. With the win, the Rays became the second team to go to the World Series after posting the worst record the year before, joining the 1991 Atlanta Braves, who went on to lose to the Minnesota Twins.[19]