2010 NCAA Division I baseball tournament

Conference champions from 30 Division I conferences earned automatic bids to regionals. The remaining 34 spots were awarded to schools as at-large invitees.

Hosted by Clemson at Doug Kingsmore Stadium

NOTE: Because Vrooman Field at Charles Watson Stadium was inadequate for NCAA postseason play, Coastal Carolina-hosted games were played at BB&T Coastal Field.

Hosted by Florida State at Dick Howser Stadium

The CWS uses two four-team brackets with double elimination format; teams play games until they accumulate two losses and no team may play a team from the other bracket. The winners of the two four-team brackets play a best-of-three series for the championship.

• * Denotes extra innings

The following players were members of the College World Series All-Tournament Team.

• 15 of 16 No. 1 seeds won their first-round games, with Cal State Fullerton being the only No. 1 seed to lose (3-1 to No. 4 Minnesota).
• Eight No. 3 seeds (half the field) won their first-round games in upsets.

• 13 of 16 No. 1 seeds won their first 2 games. The others were: No. 4 Minnesota, No. 2 Clemson and No. 2 College of Charleston
• Two No. 2 seeds were eliminated in two games: No. 2 California and No. 2 Stanford

• 13 No. 1 seeds and three No. 2 seeds advanced to the Super Regional; no No. 3 or No. 4 seeds advanced.
• Georgia Tech (No. 8) and Louisville (No. 7) were the only national seeds to not advance to the Super Regional.

• TCU qualified for its first ever College World Series by beating Texas.
• Only 3 of 8 National Seeds qualified for the College World Series.

• NCBWA (National College Baseball Writers Association) named TCU Head coach Jim Schlossnagle the 2010 National Coach of the Year.[1]
• Collegiate Baseball and Baseball America named South Carolina Head coach Ray Tanner the 2010 National Coach of the Year.[2][3]
• UCLA head coach John Savage was named the national Coach of the Year by College Baseball Insider.[4]
• South Carolina received the Opening Ceremonies award for highest team GPA (3.12) of the eight schools that made it to Omaha.
• Only one team from the 2009 CWS, Arizona State, returned for 2010.
• This was the 18th consecutive year that the SEC has fielded at least one team in the College World Series.
• South Carolina pitcher Matt Price (first team) and first baseman Christian Walker (second team) were named Freshman All-Americans by Baseball America.
• UCLA center fielder Beau Amaral, who led the Bruins with a .354 batting average in 64 games, was named a second-team Freshman All-America selection by Baseball America.
• UCLA pitchers Trevor Bauer and Gerrit Cole were named to the 2010 College All-America Team (second-team and third-team, respectively) by Baseball America.

• TCU played in its first College World Series in school history.
• Florida was the first team eliminated after its 8–5 loss to in-state rival Florida State.
• Arizona State was eliminated after two games and became the first No. 1 overall seed team to go 0–2 in the CWS under the current 64-team format.
• Florida State had a season-high 5 errors in its second loss to TCU.
• In the first meeting between South Carolina and Oklahoma, the game was scheduled to start at 2:00 pm, but due to multiple weather delays the game did not end until after 11:00 pm.

• None of the four semi-finalists, UCLA, TCU, South Carolina and Clemson, had won a previous CWS title.
• This CWS was the first since 2005 to feature an in-state rivalry in the final four with the meeting of South Carolina and Clemson.
• Trevor Bauer, with 13 strikeouts on June 26, led the nation with 165 strikeouts; UCLA led all schools with 700 strikeouts.

• UCLA played for its first-ever national championship in baseball (South Carolina had played in three previous Championship Games, 1975, 1977 and 2002).
• More than 300,000 fans attended the men's CWS for the fourth consecutive year, and the total attendance of 330,922 ranks second all-time.
• South Carolina won its first NCAA team national championship in any men's sport.
• UCLA's runner-up finish was the best in program history.
• Final game was the first championship to be decided in extra innings since 1970, and fifth all-time.
• Whit Merrifield's 11th-inning RBI single was the first walk-off to decide a championship since 2000.
• South Carolina became only the third school to win a CWS title after losing their opening game since the two-bracket format was adopted.
• South Carolina set a CWS record with six straight wins after losing their first game, and became only the third school ever to record six victories in a CWS.
• The CWS ended June 29, the latest ending date for the tournament. That record was broken in 2016.