2011 Liquigas–Cannondale season

Basso won the Gran Premio di Lugano in late February. After Caruso launched an attack that effectively softened the field, Basso's winning move came as his teammate was caught. He drew Geox–TMC's Fabio Duarte with him, and defeated him in the sprint 16 seconds ahead of the front of the remaining field.[18] The team came to the first monument race of the season, Milan–San Remo, without a real field sprinter, despite that race's tendency to end in a sprint. When a crash occurred on the Le Manie climb 90 km (56 mi) from the finish line, effectively splitting the race into two groups, Nibali and BMC Racing Team captain Alessandro Ballan struck a deal wherein both squads would send men to the front of the leading group. This was both to keep the group out ahead of the second so that sprinters left behind like Óscar Freire, Mark Cavendish, and Tyler Farrar would not be able to contest the win, but also to potentially get rid of the few sprinters that had made the split, namely Tom Boonen, Alessandro Petacchi, and Heinrich Haussler.[19] The tactic was successful; BMC Racing Team and Liquigas-Cannondale, along with Omega Pharma–Lotto and FDJ, effectively drove the leading group such that their advantage never fell below one minute. Nibali tried to attack for victory on the Poggio, knowing that even among the small group that was left he was not likely to have the best finishing sprint. Seven riders followed his acceleration, and all seven eventually passed him, leaving Nibali eighth on the day.[20] After Peter Sagan had showed strong form at Gent–Wevelgem, the squad was touted as fielding contenders at the second monument race, the Tour of Flanders.[21][22] The squad failed to be at all competitive, however; only Koren and Oss finished the race, with six others, including Sagan, abandoning before the conclusion.[23] Their best-placed rider being 95th was criticized as a major disappointment.[24] Nibali rode Liège–Bastogne–Liège as his final tune-up prior to the Giro d'Italia. While race winner Philippe Gilbert and the Schleck brothers, who rounded out the podium with the Belgian, slipped away on the Côte de Roche aux Faucons and were not caught, Nibali instigated the chase group that formed on the Côte de Saint-Nicolas. He finished eighth.[25] Afterward, he said he was satisfied with his performance, since he had not gone into the red to follow Gilbert and the Schlecks and put in a good ride on the last climb. He was, however, spent from his effort on the Côte de Saint-Nicolas and could not sprint for fourth place.[26]

The team also sent squads to the Montepaschi Strade Bianche, the GP Miguel Indurain, Paris–Roubaix, the Amstel Gold Race, La Flèche Wallonne and the Giro di Toscana, but placed no higher than 11th in any of these races.

The team also sent squads to the Clásica de San Sebastián, Tre Valli Varesine, Trofeo Melinda, GP Ouest-France, the Grand Prix Cycliste de Montréal, the Memorial Marco Pantani, the Gran Premio Bruno Beghelli and the Amstel Curaçao Race, but placed no higher than 11th in any of these races.

Reigning Giro champion Basso will not defend his title, preferring to focus on the Tour de France. He had for a time considered riding the Giro in a supporting role to Nibali, who will ride as the squad's captain. Team management decided that in the interests of respecting the race, they would not have Basso ride but be unable (due to saving himself for the Tour) to give full effort in the Giro's most difficult stages.