3-Methyluridine

The chemical compound 3-methyluridine, also called N3-methyluridine, is a pyrimidine nucleoside (abbreviated m3U). In living organisms it is present as RNA modification which has been detected in 23S rRNA of archaea, 16S and 23S rRNA of eubacteria, and 18S, 25S, and 28S of eukaryotic ribosomal RNAs.[1]

3-Methyluridine
Names
IUPAC name
3-Methyluridine
Systematic IUPAC name
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4(1H,3H)-dione
Other names
N3-Methyluridine; N-3-Methyluridine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1
    Key: UTQUILVPBZEHTK-ZOQUXTDFSA-N
  • CN1C(=O)C=CN(C1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
Properties
C10H14N2O6
Molar mass 258.230 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Desaulniers, Jean-Paul; Chui, Helen M.-P.; Chow, Christine S. (2005-12-15). "Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine". Bioorganic & Medicinal Chemistry. 13 (24): 6777–6781. doi:10.1016/j.bmc.2005.07.061. ISSN 0968-0896. PMID 16125393.
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