3-Oxetanone

3-Oxetanone, also called oxetan-3-one or 1,3-epoxy-2-propanone, is a chemical compound with formula C3H4O2. It is the ketone of oxetane, and an isomer of β-propiolactone.

3-Oxetanone
Skeletal formula
Skeletal formula
Ball-and-stick model
Ball-and-stick model
Names
Preferred IUPAC name
Oxetan-3-one
Other names
1,3-Epoxy-2-propanone
1,3-Epoxypropanone
1,3-Epoxy-2-propan-2-one
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.190.619
UNII
  • InChI=1S/C3H4O2/c4-3-1-5-2-3/h1-2H2 checkY
    Key: ROADCYAOHVSOLQ-UHFFFAOYSA-N checkY
  • InChI=1/C3H4O2/c4-3-1-5-2-3/h1-2H2
    Key: ROADCYAOHVSOLQ-UHFFFAOYAK
  • O=C1COC1
Properties
C3H4O2
Molar mass 72.06 g/mol
Density 1.124 g/cm3
Boiling point 140 °C (284 °F; 413 K)
Hazards
Flash point 53 °C (127 °F; 326 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

3-Oxetanone is a liquid at room temperature, that boils at 140 °C. It is a specialty chemical,[1][2] used for research in the synthesis of other oxetanes of pharmacological interest.[3][4] Oxetan-3-one also has been the object of theoretical studies.[5][6]

See also

References
  1. Synthonix Corp., 3-Oxetanone Archived 2009-12-16 at the Wayback Machine product sheet. Accessed on 2009-07-10.
  2. SpiroChem AG, Oxetan-3-one Archived 2012-03-26 at the Wayback Machine Product Sheet - 2011-07-07
  3. Wuitschik, G.; Rogers-Evans, M.; Müller, K.; Fischer, H.; Wagner, B.; Schuler, F.; Polonchuk, L.; Carreira, E. M., Oxetanes as promising modules in drug discovery. Angew. Chem. Int. Ed. 2006, volume 45, issue 46, pp. 7736-7739. doi:10.1002/anie.200602343
  4. Wuitschik, G.; Rogers-Evans, M.; Buckl, A.; Bernasconi, M.; Marki, M.; Godel, T.; Fischer, H.; Wagner, B.; Parrilla, I.; Schuler, F.; Schneider, J.; Alker, A.; Schweizer, W. B.; Muller, K.; Carreira, E. M., Spirocyclic oxetanes: Synthesis and properties. Angew. Chem. Int. Ed. 2008, volume 47, issue 24, pp. 4512-4515. doi:10.1002/anie.200800450
  5. George M. Breuer, Roger S. Lewis, and Edward K. C. Lee (1975), Unimolecular Decomposition Rates of Cyclobutanone, 3-Oxetanone, and Perfluorocyclobutanone. An RRKM Calculation of Internally Converted Hot Molecules Journal of Physical Chemistry, volume 79, issue 19. doi:10.1021/j100586a001
  6. P. C. Martino, P. B. Shevlin and S. D. Worley (1979), The electronics structures of small strained rings. An investigation of the interaction between the oxygen and the π orbitals in 3-methyleneoxetane and 3-oxetanone. Chemical Physics Letters, Volume 68, Issue 1, pp. 237–241. doi:10.1016/0009-2614(79)80109-8
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