4-oxalocrotonate decarboxylase

The enzyme 4-oxalocrotonate decarboxylase (EC 4.1.1.77) catalyzes the chemical reaction

4-oxalocrotonate 2-oxopent-4-enoate + CO2
4-oxalocrotonate decarboxylase
Identifiers
EC no.4.1.1.77
CAS no.37325-55-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming). This enzyme is also called 4-oxalocrotonate carboxy-lyase. This enzyme participates in 3 metabolic pathways: benzoate degradation via hydroxylation, toluene and xylene degradation, and fluorene degradation.

References

    • Shingler V, Powlowski J, Marklund U (1992). "Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp strain CF600". J. Bacteriol. 174 (3): 711–24. doi:10.1128/jb.174.3.711-724.1992. PMC 206147. PMID 1732207.


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