6-Phosphogluconic acid

6-Phosphogluconic acid (6-phosphogluconate) is an intermediate in the pentose phosphate pathway and the Entner–Doudoroff pathway.

6-Phosphogluconic acid
Skeletal formula of 6-phosphogluconic acid
Space-filling model of the 6-phosphogluconic acid anion
Names
IUPAC name
6-O-Phosphono-D-gluconic acid
Systematic IUPAC name
(2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(phosphonooxy)hexanoic acid
Other names
6-Phosphogluconate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.011.882
MeSH 6-phosphogluconate
UNII
  • InChI=1S/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1 checkY
    Key: BIRSGZKFKXLSJQ-SQOUGZDYSA-N checkY
  • InChI=1/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1
    Key: BIRSGZKFKXLSJQ-SQOUGZDYBT
  • O=P(O)(O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)O
Properties
C6H13O10P
Molar mass 276.135 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

It is formed by 6-phosphogluconolactonase, and acted upon by phosphogluconate dehydrogenase to produce ribulose 5-phosphate. It may also be acted upon by 6-phosphogluconate dehydratase to produce 2-keto-3-deoxy-6-phosphogluconate.

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