Aldehyde-stabilized cryopreservation

Aldehyde-stabilized cryopreservation is a new technique for cryopreservation first demonstrated in 2016 by Robert L. McIntyre and Gregory Fahy at the cryobiology research company 21st Century Medicine, Inc. This technique use a particular implementation of fixation and vitrification that can successfully preserve a rabbit brain in "near perfect" condition at −135 °C, with the cell membranes, synapses, and intracellular structures intact in electron micrographs.[1] The technique has finally won Small Animal Brain Preservation Prize of the Brain Preservation Foundation.[2][3] The cryopreserved brain have rewarmed and found there are no serious degraduation occurred, the brain structure under electron microscopic evaluation after rewarm still preserve well.[4][5] Although these technique still yet to successfully revival of a cryopreserved brain, some researcher see this technique provide a better possible research directions in future.[6]