Aldose-1-phosphate nucleotidyltransferase

In enzymology, an aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37) is an enzyme that catalyzes the chemical reaction

NDP + alpha-D-aldose 1-phosphate phosphate + NDP-aldose
aldose-1-phosphate nucleotidyltransferase
Identifiers
EC no.2.7.7.37
CAS no.9033-61-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

Thus, the two substrates of this enzyme are NDP and alpha-D-aldose 1-phosphate, whereas its two products are phosphate and NDP-aldose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase. Other names in common use include sugar-1-phosphate nucleotidyltransferase, NDPaldose phosphorylase, glucose 1-phosphate inosityltransferase, NDP sugar phosphorylase, nucleoside diphosphosugar phosphorylase, sugar phosphate nucleotidyltransferase, nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase, sugar nucleotide phosphorylase, and NDP:aldose-1-phosphate nucleotidyltransferase. This enzyme participates in nucleotide sugars metabolism.

References

    • CABIB E, CARMINATTI H, WOYSKOVSKY NM (1965). "PHOSPHOROLYSIS OF THE PYROPHOSPHATE BOND OF SUGAR NUCLEOTIDES. II PURIFICATION AND PROPERTIES OF THE ENZYME". J. Biol. Chem. 240: 2114–21. PMID 14299635.


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