Alon Harris

Alon Harris is an American clinical scientist, professor of ophthalmology and Professor of Artificial Intelligence and Human Health,[1][2] educator, inventor and researcher in the field of ocular blood flow and its relationship to diseases of the eye. Harris served as the principal or co-principal investigator on more than 60 research grants, published more than 392 peer-reviewed articles, and wrote 23 books and 70 book chapters.[3][4] As of 2021, he holds two patents. Harris sits on the Board of Directors and the Scientific Advisory Board of The Glaucoma Foundation[5] and is the Vice Chair of International Research and Academic Affairs, co-director of the Center for Ophthalmic Artificial Intelligence and Human Health at Mount Sinai Hospital, and Director of the Ophthalmic Vascular Diagnostic and Research Program at Icahn School of Medicine at Mount Sinai.[6]

Alon Harris
EducationIndiana University
Occupation(s)Clinical Scientist
Professor of Ophthalmology
ChildrenJonathan and Danielle
Medical career
InstitutionsIcahn School of Medicine at Mount Sinai

Visiting Professorships

Lithuanian University of Health Sciences, Lithuania
Ben Gurion University Medical Center, Be’er Sheva, Israel
Tel Aviv University
ResearchOphthalmology

Career and education

Harris's post-doctorate training in medical science physiology was at Indiana University in 1990. He received an MS in 1985 and PhD in 1988 in human performance/physiology. Subsequently he took positions at Indiana University School of Medicine, including the Lois Letzter Endowed Chair in Ophthalmology,[7] Professor of Ophthalmology, Professor of Cellular and Integrative Physiology, and Director, Glaucoma Research and Diagnostic Center, Department of Ophthalmology.[8][9] He served as Director of Clinical Research at the Glick Eye Institute.[10][11] Harris was co-chair, World Glaucoma Congress Consensus on Ocular Blood Flow,[12] and was a member of the international faculty board of the PhD program in Experimental Medicine, University of Pavia.

Research

Harris's clinical research focus includes: ocular blood flow;[13] glaucoma; intraocular pressure and hemodynamics related to eye disorders;[14] ophthalmic risk factor assessment; structural and functional progression monitoring; non-evasive imaging of diseases such as glaucoma; brain and eye physiology; modeling for factors that increase or decrease disease susceptibilities in terms of race, gender, and conditions such as diabetes.[8][15][16]

In collaboration with mathematicians, Harris uses modeling and artificial intelligence applications to increase precision of diagnostics and disease management.[1]

Grants

Harris has multiyear support from the National Science Foundation, grants from the NIH, American Diabetes Association and National Eye Institute. As of 2020, he has served as co-investigator or principal investigator (PI) on more than 60 grants related to ocular vascular physiology.[17][18][19][7] He was co-PI on The Thessaloniki Eye Study, reportedly ophthalmology's largest population-based study.[12]

Patents

Harris is co-inventor on an international patent application, Methods and systems for patient specific identification and assessment of ocular disease risk factors and treatment efficacy,[20]

He developed and generated data for two patents: "Treatment of Macular Edema"[21] and "Method to increase retinal and optical nerve head blood flow velocity in order to preserve sight."[22][23]

Publications

Editorial boards

Harris is the founder and co-editor of Modeling and Artificial Intelligence in Ophthalmology (formerly Journal of Modeling in Ophthalmology).[24][25] As of 2020, he is also on the board of the Journal of Ophthalmology,[26] Acta Ophthalmologica Scandinavica,[27] Journal of Glaucoma,[28] and PLOS ONE.[29]

Books and book chapters

Partial list:

  • Ocular blood flow in glaucoma, World Glaucoma Association Consensus Series 6 (Kugler Publications, Amsterdam, the Netherlands. 2009. ISBN 90-6299-222-6
  • Optic nerve blood flow measurement. Ophthalmology: Fifth Edition ISBN 9780323528191
  • Ocular Fluid Dynamics: Anatomy, Physiology, Imaging Techniques, and Mathematical Modeling (Modeling and Simulation in Science, Engineering and Technology) Author: Giovanna Guidoboni (Editor), Alon Harris (Editor), Riccardo Sacco (Editor) Nov 26, 2019 ISBN 303-0-25885-8
  • Biophysical Properties in Glaucoma: Diagnostic Technologies Author: Ingrida Januleviciene (Editor), Alon Harris (Editor) Nov 13, 2018 ISBN 331-9-98197-8
  • Atlas of Ocular Blood Flow: Vascular Anatomy, Pathophysiology, and Metabolism Author: Alon Harris MSc PhD Apr 07, 2010 2nd Edition ISBN 143-7-71737-3
  • Retina and Optic Nerve Imaging Author: Thomas A. Ciulla (Editor), Carl D. Regillo (Editor), Alon Harris (Editor) Aug 25, 2003 1st Edition ISBN 078-1-73433-9
  • Atlas of Ocular Blood Flow: Vascular Anatomy, Pathophysiology, and Metabolism Author: Alon Harris MSc PhD, Christian Jonescu-Cuypers PhD MD, Larry Kagemann MS BME Aug 08, 2003 1st Edition ISBN 075-0-67368-0
  • Leki generyczne w okulistyce Author: Harris Alon ISBN 836-1-25770-5

Peer-reviewed papers

Google Scholar reports that Harris's publications are cited 18,871 times, that he has an h-index of 75 and an i10-index of 280.[4]

Partial list of peer-reviewed papers:

  • Ocular blood flow as a clinical observation: Value, limitations and data analysis; Alon Harris, Giovanna Guidoboni, Brent Siesky, Sunu Mathew, Alice C Verticchio Vercellin, Lucas Rowe, Julia Arciero, Prog Retin Eye Res 2020 Jan 24;100841 PMID 31987983
  • Intraocular pressure, blood pressure, and retinal blood flow autoregulation: a mathematical model to clarify their relationship and clinical relevance; Guidoboni G, Harris A, Cassani S, Arciero J, Siesky B, Amireskandari A, Tobe L, Egan P, Januleviciene I, Park J. Invest Ophthalmol Vis Sci. 2014 May 29;55(7):4105-18. doi: 10.1167/iovs.13-13611. Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6247. PMID 24876284
  • Color Doppler analysis of ocular vessel blood velocity in normal-tension glaucoma; A Harris, RC Sergott, GL Spaeth, JL Katz… - American journal of ophthalmology, 1994[30] Cited by 392 related articles
  • Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart; P Wu, J Sato, Y Zhao, J Jaskiewicz, MK POPOV… - Biochemical Journal, 1998[31] Cited by 318 related articles
  • Color Doppler ultrasound imaging of theeye and orbit; TH Williamson, A Harris - Survey of ophthalmology, 1996[32] Cited by 294 related articles
  • Automatic retinal oximetry; SH Hardarson, A Harris, RA Karlsson, GH Halldorsson… - Investigative ophthalmology & visual science, 2006[33] Cited by 262 related articles
  • Ginkgo biloba extract increases ocular blood flow velocity; HS Chung, A Harris, JK Kristinsson, TA Ciulla… - Journal of ocular pharmacology and therapeutics, 1999[34] Cited by 220 related articles
  • Vascular aspects in the pathophysiology of glaucomatous optic neuropathy; HS Chung, A Harris, DW Evans, L Kagemann… - Survey of ophthalmology,1999[35] Cited by 209 related articles

Memberships and awards

Partial list of honors and awards:

  • Expertscape ranking in the top 0.059% of experts in the filed of glaucoma -- 2023[36]
  • The Bruno Boles Carenini Lecture Award, Italian Association for the Study of Glaucoma (AISG) – 2020
  • Glenn W. Irwin Jr., MD., Experience Excellence Recognition Award – 2002
  • William and Mary Greve International Research Scholar Award from the Research to Prevent Blindness organization[7] – 1995
  • American Academy of Ophthalmology Achievement Award – 2001[8]
  • Edmund Benjamin Spaeth Oration Award for Outstanding Clinical Research[7] – 1995

As of 2020, memberships include:

  • 2019–present: Member, The New York Glaucoma Society
  • Co-chair, the 2009 World Glaucoma Association Consensus[37]
  • 2008–present: Founding Charter Member, Von Graefe Society
  • 2008: Subcommittee on Blood Flow in Glaucoma Member, World Glaucoma Association
  • 2000–present: Honorary Member, Greek Glaucoma Society
  • 2000–present: Honorary Member, Lithuanian Glaucoma Society
  • 2000–present: Member, Israeli Glaucoma Society
  • 1996–present: Member, American Glaucoma Society[38]
  • 1995–present: Fellow, American Society for Laser Medicine and Surgery, Inc.
  • 1993–present: Member, International Society of Spaeth Fellows[12]
  • 1992–present: Member, Association for Research in Vision and Ophthalmology

See also

References
  1. Guidoboni, Giovanna; Chong, Rachel Shujuan; Marazzi, Nicholas; Chee, Miao Li; Wellington, Jessica; Lichtenegger, Emily; Cheng, Ching-Yu; Harris, Alon (2020-06-10). "A mechanism-driven algorithm for Artificial Intelligence in ophthalmology: understanding glaucoma risk factors in the Singapore Eye Diseases Study". Investigative Ophthalmology & Visual Science. 61 (7): 619. ISSN 1552-5783. Archived from the original on 2020-06-20. Retrieved 2021-04-05.
  2. "Alon Harris | Icahn School of Medicine". Icahn School of Medicine at Mount Sinai. Retrieved 2023-06-11.
  3. "Alon Harris, MS, PhD, FARVO – The Glaucoma Foundation". Archived from the original on 2022-02-20. Retrieved 2022-02-20.
  4. "Alon Harris". scholar.google.com. Archived from the original on 2022-02-22. Retrieved 2020-11-16.
  5. "Board of Directors – The Glaucoma Foundation". Archived from the original on 2022-02-19. Retrieved 2022-02-19.
  6. "Alon Harris | Mount Sinai - New York". Mount Sinai Health System. Archived from the original on 2021-09-03. Retrieved 2020-11-29.
  7. "Elections: Member Listing: Alliance of Distinguished and Titled Professors". alliance.iu.edu. Archived from the original on 2020-08-16. Retrieved 2020-12-14.
  8. "Alon Harris". PracticeUpdate. Archived from the original on 2021-01-25. Retrieved 2020-11-28.
  9. "Alon Harris, Professor of Ophthalmology, Eugene and Marilyn Glick Eye Institute". 10times.com. Archived from the original on 2022-02-22. Retrieved 2020-11-29.
  10. "Glick Eye Institute Sponsors Second Annual Vision Research Symposium". news. 2011-04-14. Archived from the original on 2020-11-27. Retrieved 2020-11-29.
  11. "Does Diabetes Cause Glaucoma?". Diabetes Forecast. Archived from the original on 2020-11-27. Retrieved 2020-12-08.
  12. "SCIENCEBASED HEALTH WELCOMES TWO NEW MEMBERS TO ITS SCIENTIFIC ADVISORY BOARD: JEFFREY BLUMBERG, PhD, FACN, FASN, CNS AND ALON HARRIS, MS, PhD, FARVO" (PDF). sciencebasedhealth. October 18, 2011. Archived (PDF) from the original on January 20, 2013. Retrieved December 14, 2020.
  13. Shoshani, Yochai Z.; Harris, Alon; Siesky, Brent A. (2010-04-01). "Advances in the understanding of ocular blood flow in glaucoma". Expert Review of Ophthalmology. 5 (2): 189–200. doi:10.1586/eop.10.17. ISSN 1746-9899. S2CID 71507020.
  14. "Alon Harris". Indiana University School of Medicine. Retrieved 2020-11-28.
  15. "The Association for Research in Vision and Ophthalmology-". www.arvo.org. Archived from the original on 2021-04-12. Retrieved 2020-11-29.
  16. Harris, Alon. "African and European Descent, Ocular Blood Flow and Glaucoma Progression". Archived from the original on 2022-02-22. Retrieved 2021-04-05. {{cite journal}}: Cite journal requires |journal= (help)
  17. Bio, Qlaris. "Innovative ocular therapeutics". Qlaris Bio. Archived from the original on 2020-11-27. Retrieved 2020-11-29.
  18. "Grantome: Search". Grantome. Archived from the original on 2020-12-08. Retrieved 2020-12-08.
  19. "Drs. Giovanna Guidoboni and Alon Harris, Indiana University". EurekAlert!. Retrieved 2020-12-08.
  20. WO 2016191277, Harris, Alon & Guidoboni, Giovanna, "Methods and systems for patient specific identification and assessment of ocular disease risk factors and treatment efficacy", published 2016-12-01, assigned to Indiana University Research & Technology Corporation
  21. US 6046223, Sponsel, William Eric & Harris, Alon, "Treatment of macular edema", published 2000-04-04, assigned to Advanced Research & Technology Institute
  22. "Alon Harris, MS, PhD, FARVO – The Glaucoma Foundation". Archived from the original on 2022-02-20. Retrieved 2022-02-19.
  23. US 5789435, Harris, Alon & Sponsel, William Eric, "Method to increase retinal and optical nerve head blood flow velocity in order to preserve sight", published 1998-08-04, assigned to Advanced Research & Technology Institute
  24. "Editorial Team | Modeling and Artificial Intelligence in Ophthalmology". www.modeling-ophthalmology.com. Archived from the original on 2020-10-24. Retrieved 2020-11-29.
  25. "About the Journal | Modeling and Artificial Intelligence in Ophthalmology". www.modeling-ophthalmology.com. Archived from the original on 2020-11-28. Retrieved 2020-11-29.
  26. "Madridge Publishers". madridge.org. Archived from the original on 2020-11-25. Retrieved 2020-11-28.
  27. "Acta Ophthalmologica". Wiley Online Library. doi:10.1111/(ISSN)1755-3768. Archived from the original on 2021-08-23. Retrieved 2020-12-17.
  28. "Editorial Board : Journal of Glaucoma". journals.lww.com. Archived from the original on 2020-09-24. Retrieved 2020-12-17.
  29. Fang, I-Mo; Chen, Li-Li (2020-09-29). "Association of macular choroidal thickness with optical coherent tomography morphology in patients with idiopathic epiretinal membrane". PLOS ONE. 15 (9): e0239992. Bibcode:2020PLoSO..1539992F. doi:10.1371/journal.pone.0239992. ISSN 1932-6203. PMC 7523999. PMID 32991629.
  30. Harris, A.; Sergott, R. C.; Spaeth, G. L.; Katz, J. L.; Shoemaker, J. A.; Martin, B. J. (1994-11-01). "Color Doppler Analysis of Ocular Vessel Blood Velocity in Normal-tension Glaucoma". American Journal of Ophthalmology. 118 (5): 642–649. doi:10.1016/S0002-9394(14)76579-1. ISSN 0002-9394. PMID 7977577. Archived from the original on 2022-02-22. Retrieved 2021-04-05.
  31. Wu, Pengfei; Sato, Juichi; Zhao, Yu; Jaskiewicz, Jerzy; Popov, M. Kirill; Harris, A. Robert (1998-01-01). "Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart". Biochemical Journal. 329 (1): 197–201. doi:10.1042/bj3290197. ISSN 0264-6021. PMC 1219032. PMID 9405294.
  32. Williamson, Tom H.; Harris, Alon (1996-01-01). "Color Doppler ultrasound imaging of theeye and orbit". Survey of Ophthalmology. 40 (4): 255–267. doi:10.1016/S0039-6257(96)82001-7. ISSN 0039-6257. PMID 8658337. Archived from the original on 2022-02-22. Retrieved 2021-04-05.
  33. Hardarson, Sveinn Hakon; Harris, Alon; Karlsson, Robert Arnar; Halldorsson, Gisli Hreinn; Kagemann, Larry; Rechtman, Ehud; Zoega, Gunnar Már; Eysteinsson, Thor; Benediktsson, Jon Atli; Thorsteinsson, Adalbjorn; Jensen, Peter Koch (2006-11-01). "Automatic Retinal Oximetry". Investigative Ophthalmology & Visual Science. 47 (11): 5011–5016. doi:10.1167/iovs.06-0039. ISSN 1552-5783. PMID 17065521. Archived from the original on 2021-04-17. Retrieved 2021-04-05.
  34. Chung, Hak Sung; Harris, Alon; Kristinsson, Jóhannes Kári; Ciulla, Thomas A.; Kagemann, Carol; Ritch, Robert (1999-06-01). "Ginkgo biloba Extract Increases Ocular Blood Flow Velocity". Journal of Ocular Pharmacology and Therapeutics. 15 (3): 233–240. doi:10.1089/jop.1999.15.233. ISSN 1080-7683. PMID 10385132. Archived from the original on 2022-02-22. Retrieved 2021-04-05.
  35. Chung, Hak Sung; Harris, Alon; Evans, David W.; Kagemann, Larry; Garzozi, Hanna J.; Martin, Bruce (1999-06-01). "Vascular Aspects in the Pathophysiology of Glaucomatous Optic Neuropathy". Survey of Ophthalmology. 43: S43–S50. doi:10.1016/S0039-6257(99)00050-8. ISSN 0039-6257. PMID 10416746. Archived from the original on 2022-02-22. Retrieved 2021-04-05.
  36. "Glaucoma: Harris, A - Expertscape.com". expertscape.com. Retrieved 2023-06-19.
  37. "Alon Harris". World Glaucoma Congress 2021. Archived from the original on 2022-02-22. Retrieved 2020-11-29.
  38. "Math modeling may provide greater understanding of glaucoma risk". Ophthalmology Times. Archived from the original on 2020-10-24. Retrieved 2020-11-29.
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