BZIP intron plant

The bZIP intron plant is an unconventional bZIP intron in plants located in the mRNA of bZIP60 orthologs. The consensus RNA structure is very similar to the animal variant with short, usually 23 nt intron defined by the loop regions of the conserved hairpins.[1] Majority of the plants contain also a nested spliceosomal intron located at the base of 3’ hairpin. The unconventional splicing in this group is performed by IRE1 in response to ER stress and it was first described in Arabidopsis thaliana.[2][3]

Consensus secondary structure and sequence conservation of bZIP intron in plants

References
  1. Hooks KB, Griffiths-Jones S (2011). "Conserved RNA structures in the non-canonical Hac1/Xbp1 intron". RNA Biol. 8 (4): 552–556. doi:10.4161/rna.8.4.15396. PMC 3225973. PMID 21593604.
  2. Deng, Y.; Humbert, S.; Liu, J.-X.; Srivastava, R.; Rothstein, S. J.; Howell, S. H. (2011). "Heat induces the splicing by IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein response in Arabidopsis". Proceedings of the National Academy of Sciences. 108 (17): 7247–7252. Bibcode:2011PNAS..108.7247D. doi:10.1073/pnas.1102117108. ISSN 0027-8424. PMC 3084119. PMID 21482766.
  3. Nagashima, Yukihiro; Mishiba, Kei-ichiro; Suzuki, Eiji; Shimada, Yukihisa; Iwata, Yuji; Koizumi, Nozomu (2011). "Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor". Scientific Reports. 1 (1): 29. Bibcode:2011NatSR...1E..29N. doi:10.1038/srep00029. ISSN 2045-2322. PMC 3216516. PMID 22355548.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.