MC21-A
MC21-A (bromophene) is an bactericidal antibiotic isolated from the O-BC30 strain of a new marine bacterium, Pseudoalteromonas phenolica.[1]
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Names | |
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Preferred IUPAC name
3,3′,5,5′-Tetrabromo[1,1′-biphenyl]-2,2′-diol | |
Other names
Bromophene; 2,2'-Dihydroxy-3,3',5,5'-tetrabromobiphenyl; 3,3',5,5'-Tetrabromo-2,2'-biphenyldiol | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.161.669 |
MeSH | 3,3',5,5'-tetrabromo-2,2'-biphenyldiol |
PubChem CID |
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RTECS number |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C12H6Br4O2 | |
Molar mass | 501.794 g·mol−1 |
Appearance | Cryst. (CHCl3) |
Melting point | 205 to 207 °C (401 to 405 °F; 478 to 480 K) |
Sol. MeOH, CHCl3 insol. H2O, hexane | |
Related compounds | |
Related biphenyls |
MC21-B Polybrominated biphenyl |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
References
- Isnansetyo, Alim; Kamei, Yuto (February 2003). "MC21-A, a Bactericidal Antibiotic Produced by a New Marine Bacterium, Pseudoalteromonas phenolica sp. nov. O-BC30T, against Methicillin-Resistant Staphylococcus aureus". Antimicrobial Agents and Chemotherapy. Washington, DC: American Society for Microbiology. 47 (2): 480–488. doi:10.1128/AAC.47.2.480-488.2003. ISSN 1098-6596. OCLC 678833406. PMC 151744. PMID 12543647.
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