MC21-B

MC21-B is an antibiotic isolated from the O-BC30T strain of a marine bacterium, Pseudoalteromonas phenolica.[1] MC21-B is cytotoxic to human leukaemia cells and human normal dermal fibroblasts.[2]

MC21-B
Names
Preferred IUPAC name
2,2′,3-Tribromo[1,1′-biphenyl]-4,4′-dicarboxylic acid
Other names
2,2′,3-Tribromobiphenyl-4,4′-dicarboxylic acid
Identifiers
3D model (JSmol)
  • InChI=1S/C14H7Br3O4/c15-10-5-6(13(18)19)1-2-7(10)8-3-4-9(14(20)21)12(17)11(8)16/h1-5H,(H,18,19)(H,20,21)
    Key: BTFCVLPFWWMQRI-UHFFFAOYSA-N
  • OC(=O)c1cc(Br)c(cc1)c2c(Br)c(Br)c(cc2)C(=O)O
Properties
C14H7Br3O4
Molar mass 478.918 g·mol−1
Appearance White powder
Sol. MeOH, CHCl3
insol. H2O, hexane
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Isnansetyo, A.; Kamei, Y. (2009). "Anti-methicillin-resistant Staphylococcus aureus (MRSA) activity of MC21-B, an antibacterial compound produced by the marine bacterium Pseudoalteromonas phenolica O-BC30T". International Journal of Antimicrobial Agents. 34 (2): 131–135. doi:10.1016/j.ijantimicag.2009.02.009. PMID 19329285.
  2. Rahman, H.; Austin, B.; Mitchell, W. J.; Morris, P. C.; Jamieson, D. J.; Adams, D. R.; Spragg, A. M.; Schweizer, M. (2010). "Novel Anti-Infective Compounds from Marine Bacteria". Marine Drugs. 8 (3): 498–518. doi:10.3390/md8030498. PMC 2857357. PMID 20411112.


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