MC21-A

MC21-A (bromophene) is an bactericidal antibiotic isolated from the O-BC30 strain of a new marine bacterium, Pseudoalteromonas phenolica.[1]

MC21-A
Names
Preferred IUPAC name
3,3′,5,5′-Tetrabromo[1,1′-biphenyl]-2,2′-diol
Other names
Bromophene; 2,2'-Dihydroxy-3,3',5,5'-tetrabromobiphenyl; 3,3',5,5'-Tetrabromo-2,2'-biphenyldiol
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.161.669
MeSH 3,3',5,5'-tetrabromo-2,2'-biphenyldiol
RTECS number
  • DV5185000
UNII
  • InChI=1S/C12H6Br4O2/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)18/h1-4,17-18H
    Key: TXODBIOSWNNKJM-UHFFFAOYSA-N
  • C1=C(C=C(C(=C1Br)O)C2=CC(=CC(=C2O)Br)Br)Br
Properties
C12H6Br4O2
Molar mass 501.794 g·mol−1
Appearance Cryst. (CHCl3)
Melting point 205 to 207 °C (401 to 405 °F; 478 to 480 K)
Sol. MeOH, CHCl3
insol. H2O, hexane
Related compounds
Related biphenyls
 MC21-B
Polybrominated biphenyl
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Isnansetyo, Alim; Kamei, Yuto (February 2003). "MC21-A, a Bactericidal Antibiotic Produced by a New Marine Bacterium, Pseudoalteromonas phenolica sp. nov. O-BC30T, against Methicillin-Resistant Staphylococcus aureus". Antimicrobial Agents and Chemotherapy. Washington, DC: American Society for Microbiology. 47 (2): 480–488. doi:10.1128/AAC.47.2.480-488.2003. ISSN 1098-6596. OCLC 678833406. PMC 151744. PMID 12543647.


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