Bryan Grenfell

Bryan Thomas Grenfell OBE FRS[3] (born 1954)[1] is a British population biologist and the Kathryn Briger and Sarah Fenton Professor of Ecology and Evolutionary Biology and Public Affairs at the Princeton School of Public and International Affairs at Princeton University.[2][4]

Bryan Grenfell

OBE FRS
Born
Bryan Thomas Grenfell

(1954-12-07) 7 December 1954[1]
Alma mater
Scientific career
FieldsEpidemiology[2]
Institutions
ThesisPopulation dynamics of baleen whales and krill in the Southern Ocean (1981)
Websiteeeb.princeton.edu/people/bryan-grenfell

Education

Grenfell earned a Bachelor of Science degree with honours from Imperial College London, and DPhil in biology from the University of York in 1981.[5]

Career and research

After his DPhil, Grenfell spent a post-doctoral period at Imperial College London, with Roy Anderson, before joining the faculty at the University of Sheffield. He moved to the University of Cambridge in 1990, to the Pennsylvania State University in 2004, and then to Princeton University in 2009. He has served as a member of the Board of Governors of the Wellcome Trust (2014–2021).[6][7]

Grenfell's research[2] focuses on the (often non-linear) dynamics and control of infectious diseases in humans and animals.[8][9] He has used simple epidemiological models and time series analysis to interpret large spatio-temporal datasets, elucidating the spread through time and space of acute infectious pathogens, notably measles.[10][11]

In 2004, Grenfell and colleagues coined the term phylodynamics to describe the interaction between pathogen evolutionary dynamics and the dynamics of epidemics.[12] This concept has been widely applied since, for example, in discussing how pathogens evolve in response to host immunity.[13]

Grenfell and collaborators have been extensively involved in analyzing the dynamics of the Severe Acute Respiratory Syndrome Coronavirus 2 pandemic that began in 2020. In particular, they have focused on the impact of immune life history on the future dynamics of the pandemic and the performance of vaccination strategies.[14][15]

Awards and honours

In 1991 Grenfell was awarded a T.H. Huxley Medal from Imperial College London, and in 1995 the 1995 Scientific Medal of the Zoological Society of London. He was elected a Fellow of the Royal Society (FRS) in 2004.[3] He has been a member of the American Academy of Arts and Sciences since 2006, and a Fellow of the American Association for the Advancement of Science since 2011. In 2008, he was awarded an Honorary Doctorate by the University of Sheffield. In 2022 he received the Kyoto Prize in Basic Sciences.[16]

References
  1. Anon (2016). "Grenfell, Prof. Bryan Thomas". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U10000465. (Subscription or UK public library membership required.)
  2. Bryan Grenfell publications indexed by Google Scholar
  3. Anon (2015). "Professor Bryan Grenfell OBE FRS". royalsociety.org. London: Royal Society. Archived from the original on 17 November 2015. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --"Royal Society Terms, conditions and policies". Archived from the original on 25 September 2015. Retrieved 9 March 2016.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  4. Bryan Grenfell at princeton.edu.
  5. Bryan Grenfell, Alumni Professor of the Biological Sciences, in: Science Journal, Summer 2005.
  6. Professor Bryan Grenfell and Professor Tobias Bonhoeffer join the Wellcome Trust Board of Governors Wellcome Trust, press release of July 7, 2014.
  7. Anon (2016). "Board of Governors". wellcome.ac.uk. London: Wellcome Trust. Archived from the original on 22 June 2016.
  8. Grenfell, Bryan T., and Andrew P. Dobson (eds). Ecology of infectious diseases in natural populations. Vol. 7. Cambridge University Press, 1995.
  9. Metcalf, C. Jessica E.; Farrar, Jeremy; Cutts, Felicity T.; Basta, Nicole E.; Graham, Andrea L.; Lessler, Justin; Ferguson, Neil M.; Burke, Donald S.; Grenfell, Bryan T. (2016). "Use of serological surveys to generate key insights into the changing global landscape of infectious disease". The Lancet. 388 (10045): 728–730. doi:10.1016/S0140-6736(16)30164-7. PMC 5678936. PMID 27059886.
  10. Grenfell, BT; Kappey, J; Bjornstad, ON (2001). "Travelling waves and spatial hierarchies in measles epidemics". Nature. 414 (6865): 716–723. doi:10.1038/414716a. PMID 11742391. S2CID 2805.
  11. Grenfell, Bryan T.Measles: Nonlinearity and Stochasticity in an Epidemic Metapopulation, Oxford University Press, 2008, ISBN 978-0-19-853006-0
  12. Grenfell, B. T.; Pybus, Oliver; Gog, Julia; Wood, James; Daly, Janet; Mumford, Jenny; Holmes, Edward C. (2004). "Unifying the Epidemiological and Evolutionary Dynamics of Pathogens". Science. 303 (5656): 327–332. Bibcode:2004Sci...303..327G. doi:10.1126/science.1090727. ISSN 0036-8075. PMID 14726583. S2CID 4017704.
  13. Voltz, Eric M; Koelle, Katia; Gog, Julia (2013). "Viral Phylodynamics". PLOS Computational Biology. 9 (3): e1002947. Bibcode:2013PLSCB...9E2947V. doi:10.1371/journal.pcbi.1002947. PMC 3605911. PMID 23555203.
  14. Saad-Roy, Chadi (2020). et al. "Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years". Science. 370 (6518): 811–818. Bibcode:2020Sci...370..811S. doi:10.1126/science.abd7343. PMC 7857410. PMID 32958581.
  15. Wagner, Caroline (2021). et al. "Vaccine nationalism and the dynamics and control of SARS-CoV-2". Science. 373 (6562): eabj7364. doi:10.1126/science.abj7364. PMC 9835930. PMID 34404735. S2CID 237199024.
  16. Kyoto Prize 2022
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