CSF/serum albumin ratio

CSF/serum albumin ratio is a test performed to compare the levels of albumin in the cerebrospinal fluid and the serum.

CSF/serum albumin ratio
LOINC1756-6

It is useful as a measure of the integrity of the blood–brain barrier.[1][2][3]

References
Pathophysiology sample values
BMP/ELECTROLYTES:
Na+ = 140 Cl− = 100 BUN = 20 /
Glu = 150
\
K+ = 4 CO2 = 22 PCr = 1.0
ARTERIAL BLOOD GAS:
HCO3− = 24 paCO2 = 40 paO2 = 95 pH = 7.40
ALVEOLAR GAS:
pACO2 = 36 pAO2 = 105 A-a g = 10
OTHER:
Ca = 9.5 Mg2+ = 2.0 PO4 = 1
CK = 55 BE = −0.36 AG = 16
SERUM OSMOLARITY/RENAL:
PMO = 300 PCO = 295 POG = 5 BUN:Cr = 20
URINALYSIS:
UNa+ = 80 UCl− = 100 UAG = 5 FENa = 0.95
UK+ = 25 USG = 1.01 UCr = 60 UO = 800
PROTEIN/GI/LIVER FUNCTION TESTS:
LDH = 100 TP = 7.6 AST = 25 TBIL = 0.7
ALP = 71 Alb = 4.0 ALT = 40 BC = 0.5
AST/ALT = 0.6 BU = 0.2
AF alb = 3.0 SAAG = 1.0 SOG = 60
CSF:
CSF alb = 30 CSF glu = 60 CSF/S alb = 7.5 CSF/S glu = 0.6
  1. Luque FA, Jaffe SL (2007). "Cerebrospinal fluid analysis in multiple sclerosis". Int. Rev. Neurobiol. International Review of Neurobiology. 79: 341–56. doi:10.1016/S0074-7742(07)79015-3. ISBN 978-0-12-373736-6. PMID 17531849.
  2. Anckarsäter H, Forsman A, Blennow K (July 2005). "Increased CSF/serum albumin ratio: a recurrent finding in violent offenders". Acta Neurol. Scand. 112 (1): 48–50. doi:10.1111/j.1600-0404.2005.00433.x. PMID 15932356. S2CID 32792323.
  3. Algotsson A, Winblad B (June 2007). "The integrity of the blood–brain barrier in Alzheimer's disease". Acta Neurol. Scand. 115 (6): 403–8. doi:10.1111/j.1600-0404.2007.00823.x. PMID 17511849. S2CID 21025192.


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