Caetano Reis e Sousa

Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968)[1] FRS FMedSci is a senior group leader at the Francis Crick Institute[3][4][5][6] and a professor of Immunology at Imperial College London.[7]

Caetano Reis e Sousa

Born
Caetano Maria Pacheco Pais dos Reis e Sousa

1968 (age 5455)[1]
EducationAtlantic College
Alma materImperial College London (BSc)
University of Oxford (DPhil)
AwardsEMBO Member (2006)[2]
Louis-Jeantet Prize for Medicine (2017)
Scientific career
FieldsImmunology[3]
InstitutionsFrancis Crick Institute
Imperial College London
Imperial Cancer Research Fund
National Institute of Allergy and Infectious Diseases
ThesisPhagocytosis of antigens by Langerhans cells
Doctoral advisorJonathan Austyn
Websitewww.crick.ac.uk/research/labs/caetano-reis-e-sousa

Education

Reis e Sousa was educated at Atlantic College in Wales,[6] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells, and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn.[8]

Career and research

After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain, he joined the Imperial Cancer Research Fund (ICRF) in 1998.[9] He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015.[9] He is also a professor of Immunology at Imperial College London[10][7] and honorary professor at University College London (UCL) and King's College London.[9]

Caetano's research centres on the mechanisms involved in sensing infection, cancer and tissue injury.[9] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses, fungi and dead cells.[9][11][12][13]

Awards and honours

Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO)[2] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009.[9] He was awarded the Louis-Jeantet Prize for Medicine in 2017.[1]

References

  1. "Caetano REIS E SOUSA". jeantet.ch. 4 October 2017.
  2. Anon (2006). "Caetano Reis e Sousa". people.embo.org. European Molecular Biology Organization.
  3. Caetano Reis e Sousa publications indexed by Google Scholar
  4. "Caetano Reis e Sousa: Immunobiology Laboratory". crick.ac.uk.
  5. "Researchers: Caetano Reis e Sousa". crick.ac.uk.
  6. Bashyam, Hema (2008). "Caetano Reis e Sousa: harnessing DC power". The Journal of Experimental Medicine. 205 (9): 1946–1947. doi:10.1084/jem.2059pi. ISSN 0022-1007. PMC 2526189. PMID 18762569.
  7. "Professor Caetano Reis e Sousa". Imperial College London.
  8. Reis e Sousa, Caetano Maria Pacheco Pais dos (1992). Phagocytosis of antigens by Langerhans cells (DPhil thesis). University of Oxford. OCLC 863542179. EThOS uk.bl.ethos.314901. icon of an open green padlock
  9. Anon (2019). "Professor Caetano Reis e Sousa FMedSci FRS". royalsociety.org. London: Royal Society. Archived from the original on 24 April 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  10. Caetano Reis e Sousa publications from Europe PubMed Central
  11. Diebold, S. S. (2004). "Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA". Science. 303 (5663): 1529–1531. Bibcode:2004Sci...303.1529D. doi:10.1126/science.1093616. ISSN 0036-8075. PMID 14976261. S2CID 33144196. closed access
  12. Kato, Hiroki; Takeuchi, Osamu; Sato, Shintaro; Yoneyama, Mitsutoshi; Yamamoto, Masahiro; Matsui, Kosuke; Uematsu, Satoshi; Jung, Andreas; Kawai, Taro; Ishii, Ken J.; Yamaguchi, Osamu; Otsu, Kinya; Tsujimura, Tohru; Koh, Chang-Sung; Reis e Sousa, Caetano; Matsuura, Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature. 441 (7089): 101–105. Bibcode:2006Natur.441..101K. doi:10.1038/nature04734. ISSN 0028-0836. PMID 16625202. S2CID 2270879. closed access
  13. Pichlmair, A.; Schulz, O.; Tan, C. P.; Naslund, T. I.; Liljestrom, P.; Weber, F.; Reis e Sousa, C. (2006). "RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates". Science. 314 (5801): 997–1001. Bibcode:2006Sci...314..997P. doi:10.1126/science.1132998. ISSN 0036-8075. PMID 17038589. S2CID 44366096. closed access
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