CAMSAP2

Calmodulin regulated spectrin associated protein family member 2 (CAMSAP2) is a protein that in humans is encoded by the CAMSAP2 gene.[5] It acts as a microtubule minus-end anchor, and binds microtubules through its CKK domain.[6]

CAMSAP2
Identifiers
Aliases	CAMSAP2, CAMSAP1L1, calmodulin regulated spectrin associated protein family member 2
External IDs	OMIM: 613775 MGI: 1922434 HomoloGene: 18927 GeneCards: CAMSAP2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 200,738,893 bp[1] End 200,860,704 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 136,195,861 bp[2] End 136,273,842 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in postcentral gyrus optic nerve endothelial cell middle temporal gyrus superior frontal gyrus entorhinal cortex Brodmann area 23 Brodmann area 46 Region I of hippocampus proper external globus pallidus Top expressed in otolith organ utricle superior cervical ganglion trigeminal ganglion substantia nigra secondary oocyte Region I of hippocampus proper fossa visual cortex facial motor nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule binding calmodulin binding microtubule minus-end binding spectrin binding protein binding Cellular component cytoplasm centrosome microtubule cytoskeleton cytosol microtubule end microtubule minus-end Golgi apparatus Biological process regulation of organelle organization neuron projection development microtubule cytoskeleton organization regulation of microtubule polymerization regulation of dendrite development axon development regulation of Golgi organization negative regulation of microtubule depolymerization cytoplasmic microtubule organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23271 67886 Ensembl ENSG00000118200 ENSMUSG00000041570 UniProt Q08AD1 Q8C1B1 RefSeq (mRNA) NM_001297707 NM_001297708 NM_203459 NM_001389638 NM_001081360 NM_001347109 NM_001347110 RefSeq (protein) NP_001284636 NP_001284637 NP_982284 NP_001334038 NP_001334039 Location (UCSC) Chr 1: 200.74 – 200.86 Mb Chr 1: 136.2 – 136.27 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse