Claudia Fischbach
Claudia Fischbach is a German biophysicist who is the Stanley Bryer 1946 Professor of Biomedical Engineering at Cornell University. She is Director of the Cornell Physical Sciences Oncology Centre on the Physics of Cancer Metabolism.
Claudia Fischbach | |
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Alma mater | Ludwig Maximilian University of Munich Harvard University |
Scientific career | |
Institutions | Cornell University Harvard University |
Thesis | Adipose tissue engineering development of a 3-D model system of adipogenesis (2004) |
Early life and education
Fischbach-Teschl earned a master's degree in pharmacy from the Ludwig Maximilian University of Munich. She worked toward her doctorate in pharmaceutical technology at the University of Regensburg. She then moved to Harvard University, where she worked in engineering.[1]
Research and career
In 2007, Fischbach joined Cornell University,[2] where she started using biomedical engineering to better understand how to treat cancer.[3] The progression of cancer is influenced by cellular interactions with nearby cells and the extracellular matrix. Despite that, the majority of cancer studies do not replicate conditions outside of the body. Fischbach-Teschl uses tissue engineering to design systems that let her model and investigate tumor cells. She uses model systems to understand the biological strategies tumors take to modify bodily function, become more aggressive and metastasize.[4]
Fischbach has extensively investigated the fundamental mechanisms that underpin breast cancer. For example, she showed that obesity can change the consistence of breast tissue, which can promote the disease.[5][6] She was supported by the Human Frontier Science Program to study the impact of breast cancer on bone progression [7][8] She showed that exercise, which is often prescribed to tackle bone loss, could help to protect people against cancer.[9] Her research showed that breast cancer can trigger distant bone growth, which could be a preemptive defence against metastasis.[10]
Awards and honors
- 2015 Public Voices Fellow of The OpEd Project[11]
- 2016 American Institute for Medical and Biological Engineering[12][13]
- 2017 Alexander von Humboldt Foundation[14]
- 2022 Cornell University College of Engineering EPICC Collaboration Award[15]
- 2023 Biomedical Engineering Society Cellular and Molecular Bioengineering Momentum Award[16][17]
Selected publications
- Claudia Fischbach; Ruth Chen; Takuya Matsumoto; Tobias Schmelzle; Joan S Brugge; Peter J Polverini; David J Mooney (2 September 2007). "Engineering tumors with 3D scaffolds". Nature Methods. 4 (10): 855–860. doi:10.1038/NMETH1085. ISSN 1548-7091. PMID 17767164. Wikidata Q40085983.
- Ying Zheng; Junmei Chen; Michael Craven; et al. (29 May 2012). "In vitro microvessels for the study of angiogenesis and thrombosis". Proceedings of the National Academy of Sciences of the United States of America. 109 (24): 9342–9347. Bibcode:2012PNAS..109.9342Z. doi:10.1073/PNAS.1201240109. ISSN 0027-8424. PMC 3386137. PMID 22645376. Wikidata Q30519206.
- Claudia Fischbach; Hyun Joon Kong; Susan X Hsiong; Marta B Evangelista; Will Yuen; David J Mooney (6 January 2009). "Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement". Proceedings of the National Academy of Sciences of the United States of America. 106 (2): 399–404. Bibcode:2009PNAS..106..399F. doi:10.1073/PNAS.0808932106. ISSN 0027-8424. PMC 2626714. PMID 19126683. Wikidata Q37061984.
References
- "Claudia Fischbach". mooneylab.seas.harvard.edu. Retrieved 6 January 2023.
- "Principal Investigator – THE FISCHBACH LAB". www.fischbachlab.org. Retrieved 6 January 2023.
- "Research – THE FISCHBACH LAB". www.fischbachlab.org. Retrieved 6 January 2023.
- "Claudia Fischbach | Cornell Engineering". www.engineering.cornell.edu. Retrieved 6 January 2023.
- "Stiffer breast tissue in obese women promotes tumors". Cornell Chronicle. Retrieved 6 January 2023.
- Ramanujan-Cornell, Krishna (25 August 2015). "Obesity makes breast tissue stiff and scarred". Futurity. Retrieved 6 January 2023.
- "Study to focus on breast cancer's effect on bone composition". Cornell Chronicle. Retrieved 6 January 2023.
- "Metastatic breast cancer affects bone mineral before spreading". Cornell Chronicle. Retrieved 6 January 2023.
- "Exercise could reduce bone tumor growth". Cornell Chronicle. Retrieved 6 January 2023.
- "Researchers link breast cancer and bone growth". Cornell Chronicle. Retrieved 6 January 2023.
- "Stories by Claudia Fischbach". Scientific American. Retrieved 6 January 2023.
- "Claudia Fischbach-Teschl Claudia Fischbach-Teschl, Ph.D. To be Inducted into Medical and Biological Engineering Elite - AIMBE". Retrieved 6 January 2023.
- "Claudia Fischbach-Teschl, Ph.D. COF-1951 - AIMBE". Retrieved 6 January 2023.
- "Prof. Dr. Claudia Fischbach-Teschl - Alexander von Humboldt-Stiftung".
- "EPICC Awards honor faculty, staff exemplifying college's core values | Cornell Engineering". www.engineering.cornell.edu. Retrieved 6 January 2023.
- "Claudia Fischbach-Teschl wins 2023 CMBE Momentum Award | Meinig School of Biomedical Engineering". www.bme.cornell.edu. Retrieved 6 January 2023.
- "CMBE Momentum Award - Biomedical Engineering Society". www.bmes.org. Retrieved 6 January 2023.