Cryptosporidium muris

Cryptosporidium muris is a species of coccidium, first isolated from the gastric glands of the common mouse.[1] Cryptosporidium does originate in common mice, specifically laboratory mice. However, it also has infected cows, dogs, cats, rats, rabbits, lambs, and humans and other primates.

Cryptosporidium muris
Scientific classification Edit this classification
Domain: Eukaryota
Clade: Diaphoretickes
Clade: SAR
Clade: Alveolata
Phylum: Apicomplexa
Class: Conoidasida
Order: Eucoccidiorida
Family: Cryptosporidiidae
Genus: Cryptosporidium
Species:
C. muris
Binomial name
Cryptosporidium muris
Tyzzer, 1910

General characteristics

Cryptosporidium muris infects dogs, rabbits, lambs, cats, humans, and non-human primates.[2] This type of cryptosporidium infects people and animals by the oocyst acquired in water. If people or animals drink the water, then they could become infected and then complete the cycle by passing oocysts. People and animals can also become infected by being in water that has the oocysts present. The area where Cryptosporidium muris most commonly occurs is in Kenya, France, Thailand, and Indonesia. It also occurs in the western hemisphere but to a far lower amount.

Diagnostics and prevention

The current diagnostics for Cryptosporidium muris are Polymerase Chain Reaction (PCR), Restriction Fragment Length Polymorphism (RFLP), and DNA sequencing. Diagnostic tests can be frustrating as it is highly difficult to differentiate between species and the treatment would be the same for all species. Cryptosporidium muris is resistant to disinfectants; it has been discovered that ultraviolet or UV light helps to kill the species.[3] As for prevention, people should not drink infected water or play in it. Also making sure to practice good hygiene improves the risks of not contracting Cryptosporidium.[4]

Prevalence

Cryptosporidium muris has prevalence in the following species in the following amount: Dairy Cows -68% Feedlot Cows- 80% Mice- 26%, and Rats- 5%.[5]

References
  1. Tyzzer EE (1910). "An extracellular Coccidium, Cryptosporidium Muris (Gen. Et Sp. Nov.), of the gastric Glands of the Common Mouse". J Med Res. 23 (3): 487–510.3. PMC 2098948. PMID 19971982.
  2. Gatei, Wangeci; Ashford, R. W.; Beeching, N. J.; Kamwati, S. K.; Greensill, J.; Hart, C. A. (2002). "Cryptosporidium muris Infection in an HIV-Infected Adult, Kenya". Emerging Infectious Diseases. 8 (2): 204–206. doi:10.3201/eid0802.010256. PMC 2732451. PMID 11897075.
  3. Palmer, Carol J.; Xiao, Lihua; Terashima, Angélica; Guerra, Humberto; Gotuzzo, Eduardo; Saldías, Gustavo; Bonilla, J. Alfredo; Zhou, Ling; Lindquist, Alan; Upton, Steve J. (2003). "Cryptosporidium muris, a Rodent Pathogen, Recover from Human in Peru". Emerging Infectious Diseases. Center for Disease Control and Prevention. 9 (9): 1174–1176. doi:10.3201/eid0909.030047. PMC 3016761. PMID 14519260.
  4. Chappell CL, Okhuysen PC, Langer-Curry RC, Lupo PJ, Widmer G, Tzipori S (2015). "Cryptosporidium muris: Infectivity and Illness in Healthy Adult Volunteers". Am. J. Trop. Med. Hyg. 92 (1): 50–5. doi:10.4269/ajtmh.14-0525. PMC 4347390. PMID 25311695.
  5. Anderson, B. C (1991). "Prevalence of Cryptosporidium muri-like oocysts among cattle populations of the United States: Preliminary report". The Journal of Protozoology. 38 (6): 14S–15S. PMID 1818141.

Further reading


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