D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase
D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase (EC 2.7.7.71, hddC (gene), gmhD (gene)) is an enzyme with systematic name GTP:D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction
- D-glycero-alpha-D-manno-heptose 1-phosphate + GTP GDP-D-glycero-alpha-D-manno-heptose + diphosphate
| D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.71 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose.
References
- Kneidinger B, Graninger M, Puchberger M, Kosma P, Messner P (June 2001). "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry. 276 (24): 20935–44. doi:10.1074/jbc.m100378200. PMID 11279237.
External links
- D-glycero-alpha-D-manno-heptose+1-phosphate+guanylyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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