Dermal cylindroma

In dermatologic pathology, a dermal cylindroma, also dermal eccrine cylindroma or cutaneous cylindroma[1]: 666 ) and (less specifically) cylindroma, is a benign adnexal tumor[2] that occurs on the scalp and forehead.

Dermal cylindroma
Dermal cylindroma treated with X-rays without recurrence

Multiple cylindromas may grow together in a "hat-like" configuration, sometimes referred to as a turban tumor.[3] Cylindromas are uncommon dysplasias of skin appendages.[4]

Histology

Dermal cylindromas are:

  • Dermal lesions consisting of nests of cells that are surrounded by hyaline (i.e., glassy, eosinophilic, acellular) material and have:
    • Hyperchromatic nuclei that may palisade (columnar nuclei arranged around the periphery of the cell nests with their short axis tangential to the nest periphery), and
    • Cells with lighter staining ovoid nuclei at their centre.

They lack of a significant number of lymphocytes; this differentiates them from spiradenomas.

Additional images
  • Micrograph of a dermal cylindroma in H&E stain.
    Micrograph of a dermal cylindroma in H&E stain.
  • Micrograph of dermal cylindroma in H&E stain.
    Micrograph of dermal cylindroma in H&E stain.
  • Dermal cylindroma. Puzzle-like distribution of tumour foci.
    Dermal cylindroma. Puzzle-like distribution of tumour foci.
  • Dermal cylindroma. Hyaline droplets visible in lobules.
    Dermal cylindroma. Hyaline droplets visible in lobules.
  • Dermal cylindroma, micronodular type.
    Dermal cylindroma, micronodular type.

See also

References
  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. "Cylindroma" at Dorland's Medical Dictionary
  3. "Cylindroma: Background, Pathophysiology, Epidemiology". 14 July 2021. {{cite journal}}: Cite journal requires |journal= (help)
  4. Cylindroma at eMedicine


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