Deslanoside

Deslanoside (trade name Cedilanide in Brazil[1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove.[2][3]

"Cedilanide" redirects here. Not to be confused with Cedilanid, a trade name of lanatoside C.
Deslanoside
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.037.774
Chemical and physical data
FormulaC47H74O19
Molar mass943.090 g·mol−1
  • InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 checkY
  • Key:OBATZBGFDSVCJD-LALPQLPRSA-N checkY
  (verify)

References
  1. "Cedilanide". Drugs.com.
  2. Bakke OM, Aslaksen A, Lehmann V, Lien E (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of Cardiovascular Pharmacology. 3 (5): 1015–25. doi:10.1097/00005344-198109000-00012. PMID 6168847.
  3. Budavari S, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123, 2967
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.