Dr. Katz, Professional Therapist

The show was created by Burbank, California, production company Popular Arts Entertainment (executive producers: Tim Braine and David Pritchard), with Jonathan Katz and Tom Snyder, developed and first made by Popular Arts for HBO Downtown Productions. Boston-based Tom Snyder Productions became the hands-on production company, and the episodes were usually produced by Katz and Loren Bouchard.

The show was computer-animated in a crude, easily recognizable style produced with the software Squigglevision (a device Snyder had employed in his educational animation business) in which all persons and animate objects are in color and have constantly squiggling outlines, while most other inanimate objects are static and usually shades of gray.[4] The original challenge Popular Arts faced was how to repurpose recorded stand-up comedy material. To do so, they based Dr. Katz's patients on stand-up comics for the first several episodes, simply having them recite their stand-up acts. The secondary challenge was how to affordably animate on cable TV at the time. Snyder (a boyhood friend of Braine's) had Squigglevision, an inexpensive means of getting animation on cable, which could not afford traditional animation processes. A partnership between Popular Arts, Tom Snyder Productions and Jonathan Katz was formed, and thus, Dr. Katz, Professional Therapist was born.

The first episode of Dr. Katz aired on May 28, 1995. A total of 81 episodes were produced, with the sixth and final season (of 18 episodes) beginning on June 15, 1999. Only the first six of the final season's episodes were aired on Comedy Central immediately, though they did air in international markets. After a five-month delay, another nine episodes ran during a Christmas Eve marathon. The final three episodes were broadcast for the first time in the United States on February 13, 2002, during an event dubbed "Dr. Katz goes to the Final Three."

A comic strip of the same name was produced by the Los Angeles Times Syndicate from March 1997 to January 2000. One book collection was published, Hey, I've Got My Own Problems. Writers included Bill Braudis and Dave Blazek, with artwork by Dick Truxaw.

In 2007, Comedy Central presented An Evening with Dr. Katz: Live from the Comedy Central Stage, a live-action special taped in front of a live audience at the Hudson Theater on Santa Monica Boulevard in Los Angeles, featuring Jonathan Katz reprising his role as Dr. Katz. Comedians Maria Bamford, Kathy Griffin, Andy Kindler and Paul F. Tompkins appeared in person as celebrity "clients"; Jon Benjamin and Laura Silverman reprised their respective roles from the animated series. This special was included in the "Complete Series" DVD compilation. In January 2008, live performances were presented over two nights as part of SF Sketchfest in San Francisco, California. On the first night, Jonathan Katz's guest list included Maria Bamford, Brian Posehn and Bob Odenkirk. The surprise guest that evening was Robin Williams. At the end of the "session" Katz revealed that he had multiple sclerosis in real life.[5]

The show returned to SF Sketchfest in January 2015. This performance, commemorating the 20th anniversary of the program, featured Katz with Jon Benjamin and Tom Snyder again portraying his son and therapist, respectively. The patients for this production were Ron Funches, Pete Holmes, Morgan Murphy and Emo Philips.[6] Also in 2015, live performances took place at the Moontower Comedy & Oddity Festival in Austin, Texas, on April 23 and 24. Staged therapy sessions included Andy Kindler, Emo Philips, Maria Bamford, Dom Irrera, Dana Gould, and Eddie Pepitone.[7] The show was again staged at SF Sketchfest in January 2016. The patients who booked "appointments" that night included Janeane Garofalo, Andy Kindler, Maria Bamford, The Sklar Brothers, and Chelsea Peretti.[8] As part of the 16th Annual SF Sketchfest in San Francisco there was a live performance on January 20, 2017. Katz did a short stand-up comedy set Guest "patients" included Kevin Pollak, Natasha Leggero, Tom Papa, Moshe Kasher and Scott Aukerman.[9] Leggero joined Kasher's session midway through for couples therapy. The two are married in real life.

An audio-only version of the show was produced for Audible. The first three episodes were released in June 2017 and were released Thursdays. It ran for 15 episodes. Guests have included Ray Romano, Sarah Silverman, and Ted Danson. A full-length audiobook titled Dr. Katz: The Audiobook was released as an Audible exclusive in 2018 featuring all-new content.