Ectoplasmic specialisation

Ectoplasmic specializations are actin-related cell–cell junctions present in the testicular seminiferous epithelium and occur during spermatogenesis.[1] These junctions are located at the Sertoli–Sertoli cell interface and Sertoli-elongating spermatid interface, which occur during the seminiferous epithelial cycle of spermatogenesis. There must be vast reconstructing of the anchoring junctions such as the ectoplasmic specializations within the testies. The reconstruction of these junctions is important because it facilitates the migration of the developing germ cells across the seminiferous epithelium[2]

References

  1. Mruk, DD; Cheng, CY (2004). "Cell–cell interactions at the ectoplasmic specialization in the testis". Trends Endocrinol. Metab. 15 (9): 439–447. doi:10.1016/j.tem.2004.09.009. PMID 15519891.
  2. Wong, EW; Mruk, DD; Cheng, CY (2008). "Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778 (3): 692–708. doi:10.1016/j.bbamem.2007.11.006. PMC 2701193. PMID 18068662.


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