Epidermidibacterium keratini

Epidermidibacterium keratini
Scientific classification
Domain:	Bacteria
Phylum:	Actinomycetota
Class:	Actinomycetia
Order:	Sporichthyales
Family:	Sporichthyaceae
Genus:	Epidermidibacterium; Lee et al. 2018[1]
Species:	E. keratini
Binomial name
	Epidermidibacterium keratini; Lee et al. 2018[1]
Type strain
	EPI-7; JCM 31644; KCCM 90264

Epidermidibacterium keratini is a Gram-positive, chemoheterotrophic, non-motile, non-sporeforming, rod-shaped, aerobic bacterium that it was first isolated from human epidermal keratinocytes in 2018.[1] It is part of the normal human flora, typically the skin flora.[2]

Bacteriology

Human skin provides a habitat for various microorganisms that stably maintain communities through commensal relationships.[3] And skin aging is associated with changes in cutaneous physiology including interactions with a skin microbial community.[4] This strain was first isolated from young woman. Additionally, the younger skin appeared to have high proportion of E. keratini , while the older skin had no E. keratini but rather other types of bacteria that this species has been found to be related to skin aging.[2]

References

Lee DG, Trujillo ME, Kang S, Nam JJ, Kim YJ. (2018). "Epidermidibacterium keratini gen. nov., sp. nov., a member of the family Sporichthyaceae, isolated from keratin epidermis". Int J Syst Evol Microbiol. 68: 745–750. doi:10.1099/ijsem.0.002579. PMID 29458473.
Lee YG, Lee DG, Gwag JE, Kim M, Kim M, Kim HG, et al. (March 2019). "A 1,1′-biuracil from Epidermidibacterium keratini EPI-7 shows anti-aging effects on human dermal fibroblasts". Applied Biological Chemistry. 62 (1): 14. doi:10.1186/s13765-019-0421-9.
Cogen AL, Nizet V, Gallo RL (March 2008). "Skin microbiota: a source of disease or defence?". The British Journal of Dermatology. 158 (3): 442–55. doi:10.1111/j.1365-2133.2008.08437.x. PMC 2746716. PMID 18275522.
Shibagaki N, Suda W, Clavaud C, Bastien P, Takayasu L, Iioka E, et al. (September 2017). "Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria". Scientific Reports. 7 (1): 10567. Bibcode:2017NatSR...710567S. doi:10.1038/s41598-017-10834-9. PMC 5585242. PMID 28874721.

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[Lee-1] Lee DG, Trujillo ME, Kang S, Nam JJ, Kim YJ. (2018). "Epidermidibacterium keratini gen. nov., sp. nov., a member of the family Sporichthyaceae, isolated from keratin epidermis". Int J Syst Evol Microbiol. 68: 745–750. doi:10.1099/ijsem.0.002579. PMID 29458473.

[Lee_2019-2] Lee YG, Lee DG, Gwag JE, Kim M, Kim M, Kim HG, et al. (March 2019). "A 1,1′-biuracil from Epidermidibacterium keratini EPI-7 shows anti-aging effects on human dermal fibroblasts". Applied Biological Chemistry. 62 (1): 14. doi:10.1186/s13765-019-0421-9.

[3] Cogen AL, Nizet V, Gallo RL (March 2008). "Skin microbiota: a source of disease or defence?". The British Journal of Dermatology. 158 (3): 442–55. doi:10.1111/j.1365-2133.2008.08437.x. PMC 2746716. PMID 18275522.

[4] Shibagaki N, Suda W, Clavaud C, Bastien P, Takayasu L, Iioka E, et al. (September 2017). "Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria". Scientific Reports. 7 (1): 10567. Bibcode:2017NatSR...710567S. doi:10.1038/s41598-017-10834-9. PMC 5585242. PMID 28874721.