Ethylmalonyl-CoA decarboxylase
Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) is an enzyme with systematic name (S)-ethylmalonyl-CoA carboxy-lyase (butanoyl-CoA-forming).[5] This enzyme catalyses the following chemical reaction
- (S)-ethylmalonyl-CoA butanoyl-CoA + CO2
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | ECHDC1, HEL-S-76, MMCD, dJ351K20.2, ethylmalonyl-CoA decarboxylase 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 612136 MGI: 1277169 HomoloGene: 23106 GeneCards: ECHDC1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| EC number | 7.2.4.3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Ethylmalonyl-CoA decarboxylase | |||||||||
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| Identifiers | |||||||||
| EC no. | 4.1.1.94 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The vertebrate enzyme decarboxylates ethylmalonyl-CoA.
References
- GRCh38: Ensembl release 89: ENSG00000093144 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000019883 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Linster CL, Noël G, Stroobant V, Vertommen D, Vincent MF, Bommer GT, Veiga-da-Cunha M, Van Schaftingen E (Dec 2011). "Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading". The Journal of Biological Chemistry. 286 (50): 42992–3003. doi:10.1074/jbc.m111.281527. PMC 3234807. PMID 22016388.
External links
- Ethylmalonyl-CoA+decarboxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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