FBI: Most Wanted

When ICE agent Thomas Gilman flees after killing his wife and two children with the explosion destroying his house and leaving one of his neighbors dead and two others wounded, Maggie and OA are called in to investigate the scene with the FBI's New York field office eventually contacting the Fugitive Task Force led by SSA Jess LaCroix to help arrest Gilman while determining the motive for his killings.

When Justin Brock fatally kills his wife after also shooting dead an intruder in his home with the 911 call recording everything that happened, he is placed on the Bureau's most wanted list and the FBI's Fugitive task force led by SSA Jess LaCroix is assigned to track him down. They learn that Brock gave multiple proscriptions provided by the Forsaken Sons biker gang, with whom he worked. An associate of his, upon being arrested, reveals that Brock operates another clinic in Pennsylvania under a different name. Brock transferred money to an account in Richmond, Virginia, which he plans to deposit from with the help of his estranged daughter. LaCroix and his team convince her to deposit the money herself to lure her father, after revealing to her that his military history was fake. Brock enters their trap and confronts his daughter, who outsmarts him and LaCroix talks her down from killing her father.

• Henry Thomas (Justin Brock) is credited as a Special Guest Star.

Tyrone Jackson, leader of the Rolling Sixs gang, plans to gain more power and territory and seemingly steals robbery plans from a rival gang. The Fugitive Task Force deduces a meeting place he and Cleo Wilkens shared, only to find him dead inside the water tower. They're quick to deduce that Cleo was behind the murder and that she herself wants to continue his work. As she continues her quest for power, Barnes decides to go undercover, reassuming an identify she utilised five years ago to get in touch with an old associate that leads her to Cleo. She proves her loyalty and is soon tasked to aid Cleo and her crew in a robbery, utilising the same plans that she stole disguised as Tyrone. Once the FBI raids the location, she holds Barnes' associate hostage, but she and LaCroix talk her into surrendering. LaCroix grapples with how to explain to his daughter what her mother worked with in the name of protecting her loved ones.

• Alana De La Garza (Isobel Castille) is credited as a Special Guest Star.

After the disappearance of his daughter is ignored by local PD, Reginald Waters, a Native American man decides to take matters into his own hands and the Task Force must track him down before his crusade claims lives. Waters' crusade crosses multiple state lines, pursuing a possible sex trafficking ring his daughter was forced into. In Maryland, he kidnaps a prostitute who tells him that his daughter was killed by another don. The Task Force learns that the don was later killed, and that Waters turns back to his father to stop the cycle of abuse his family endured. He takes his younger brother to his father's former reservation school outside Ontario, Canada, where they conduct a ritual to lift the curse. When surrounded, Clinton talks Waters into surrendering. His daughter's remains are later found and identified and given a proper burial.

• Martin Sensmeier (Reginald Waters) is credited as a Special Guest Star.

After taking down a terrorist who was responsible for kidnapping 26 children, the Fugitive Task Force and Special Agent OA Zidan from the New York field office as well as OA's colleagues in the New York office search for the terrorist's wife, who is determined to follow through with her husband's deadly plan while Jess attempts to find Tali who was taken by Immigration and Customs Enforcement officers when the local food bank she volunteers at was raided.

LaCroix and the Fugitive Task Force must hunt for 17-year-old Kyle Dennison and his accomplice Harris Folger who are on a rampage throughout a small town in Pennsylvania, killing people they believe oppressed them. They learn that both suffered heavy losses in the early months of the COVID-19 pandemic, with Folger losing his wife and job, while Kyle lost his disapproving father not long after his mother in a car accident. Remaining acquittances of Kyle describe him as a good person despite his involvement, and LaCroix asks his art teacher to make a message for him in addition to urging his surrender. When Folger and Kyle scope their last target, he has second thoughts and kills Folger and escapes to his mother's memorial, where the task force talks him into surrendering. LaCroix's father Byron returns to celebrate Tali's birthday, bringing a new girlfriend with him, with whom they announce that they will get married. Despite his re-emergence into LaCroix' life, the animosity between them still lingers.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

Avery Garnier is abducted from her own home after an elderly man steals from her safe and kills her husband. The task force investigate and Jess discovers similarities in the case to an old case he worked 18 years ago in 2002 when he first joined the FBI, with them learning that the fugitive is the same as back then, Maurice Hewitt. Their investigation crosses paths with the U. S. Marshals and bounty hunter Jackie Ward, who is also on the hunt for Hewitt. His murder pattern strikes anyone close to Garnier, whose real name is Elyse Shipchuck when she was placed in witness protection. As his final stand, Hewitt robs the same bank as he did 18 years ago, but traps Garnier in the process. LaCroix outsmarts him and cuffs him, and learns that Hewitt blames him for some of his actions and that he has a son. On the personal front, his relation with his father nears a boiling point and LaCroix reveals that he was upset that he didn't attend his wife's funeral. His father reveals he spent 15 months in prison for a petty crime, and ultimately decides for him and his fiancee to stay at LaCroix's sister's place.

• This episode marks the final appearance of Clinton Skye (Nathaniel Arcand) while Terry O'Quinn (Byron LaCroix) and Amy Carlson (Jackie Ward) are credited as Special Guest Stars.

The Fugitive Task Force hunts for a rogue militia group after they shoot at several native teenagers crossing into the U.S. from Canada, working together with special-agent-in-charge Mike Fritts. They quickly learn from the shooters' family that they're weapons at illegally bought and that the group has never killed before until now. They surround a radio cabin, where Rob Wahl and his uncle Paul Flanks are hiding, where Paul tries to shoot back, but is swiftly taken down, while Rob surrenders. He points them to the third shooter, Anthony Noel, a former Iraq veteran turned radical, fighting against those he seems to have invaded his country. LaCroix and his team learn that he attempted to brainwash border guard Whitney Anderson, with whom he also fathers a child. They and police surround Noel at the immigration centre in Plattsburgh, and Crosby takes him out when he charges forwards. LaCroix and his father reconcile and he asks LaCroix to forgive him and asks him to come to his wedding, which he later accepts.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

Travis Russell, a man on trial for murder, escapes before his trial starts and goes on a murder spree, seemingly targeting people who won the lottery. LaCroix and the Fugitive Task Force work with Jackie Ward, who is Russell's bonds person to capture him. Further investigation into the lottery factory, reveals that Russell had an accomplice on the inside to aid him tamper with the lottery prices in order to turn it into his ideal of lottery, but that she betrayed him and that he now seeks revenge. When his accomplice dies of food poisoning, the Task Force and Ward race to stop his second accomplice who he thinks betrayed him. Upon stopping her car, she tries to shoot Ward before Crosby tackles her. They discover Russell's body in the car, having been overpowered by the accomplice. On the personal front, LaCroix takes an interest in Tali's horseback riding teacher Sarah, but she declines his invitation for dinner.

• Amy Carlson (Jackie Ward) is credited as a Special Guest Star.

As Special Agent Ivan Ortiz from the FBI counter-terrorism unit and also a Los Angeles native joins the Fugitive task force, the team hunt for repeat offender Samuel Smith who kidnapped a young boy, Caleb Vaughner, after killing his mother and grandmother. The Task Force paints a picture of a traumatised Smith who was kept in strict line as a kid, which he later put over his victims, two of which supposedly died. They identify an accomplice of Smith, who provided him with potential victims and arrange a meeting in a parking garage. Once they surround him, they attempt to retrieve Caleb's location from Smith, but he commits suicide by jumping, claiming they'll never find Caleb. His phone triangulation leads them to an old house, where they find his second victim, Daniel Cain, alive many years after his supposed death. Cain provides them with clues to Caleb's location, who survives and hospitalised. Simultaneously Daniel is reunited with his parents. Sarah tells LaCroix she is recovering from a recent breakup and wasn't prepared for him to ask her out, which she asks him to do again, which she this time accepts.

• This episode marks the debut appearance of Ivan Ortiz (Miguel Gomez).

The Fugitive Task Force sets out to track brothers Greg and Wyatt Hammond, both placed on the Most Wanted List after they are set on getting revenge against members of Griffin Coal & Power that caused their town's environmental destruction. Their pattern of killings starts with Greg's former supervisor, a member of the HR department and another employee before they go after the company boss Larry Griffin. A bomb goes of in an art gallery which the company spent money on instead of aiding the community and the Task Force stop Wyatt from getting to Griffin's attorneys. When his daughter is kidnapped by Greg, Griffin takes matters into his own hands in order to end it all. His confrontation with Greg makes his daughter change views on him once Greg is apprehended, she decides to relinquish the land that she was set to inherit from Griffin, forcing his company to finally publicly acknowledge that they dumped illegal waste. Sarah gets to meet LaCroix's family, but his father and sister share a heated disagreement about letting her stay at their place without Jess' input. However he accepts the proposal.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

The Fugitive Task Force works with the JTTF, heads to Washington, D.C., to protect a former informant, Sheri James, of Ortiz after a hitman tries to kill her, but killing her sister instead. The case becomes personal for Ortiz who was in a relationship with Sheri, but things take a turn when she is murdered. The Task Force also deduces that Max Nikolla, who Sheri had helped Ortiz get behind bars and who was recently released from prison, wasn't responsible for her death, but solely the bombing of a marathon event. Ortiz also learns that to his dismay, Sheri had been hustling her clients, including himself, and was also pregnant. They track down the hitman, Nancy Lawson, who was paid by Indiana congressman Reese Holland, and deduces that he might be the father of Sheri's child. Holland is arrested for his involvement. Byron and Marie get married on the LaCroix farm, also attended by Jess' colleagues and Sarah. His father also encourages him to go further with his relationship with Sarah.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

As they wait for news on Kenny who is in surgery, being treated for wounds he received after he was shot by his old friend, Curtis Williams, an Army veteran who was also a hired assassin while assisting agents Maggie Bell and OA Zidan of the FBI's New York field office on a case involving the murder of a woman on federal property which also led to the uncovering of a sex trafficking ring which occurred during the FBI Season 4 premiere episode, "All That Glitters", the Fugitive Task Force are assigned to hunt down a suspect believed to be responsible for the murder of billionaire Nathan Tate which triggers a gunfight in downtown New York City that ends with both the suspect and an NYPD officer dead and has the team meeting Kristin Gaines, an agent from the FBI's Miami field office who has been investigating the suspect as well as his movements. Jess also learns that he and Kenny have been cleared of the shooting that occurred at Jess's house which also reveals that Kenny shot dead Hugh Hill, the ex-husband of Jess's girlfriend, Sarah Allen. With assistant from OA who temporarily joins the team and Kristin, they race to apprehend Colin Kent and his associates, only to discover that Kent has not only fled the mansion he was staying in via an airplane and is heading to an unknown location but that he now has information concerning the identities of those involved in the ring.

As Hana rejoins the team while struggling to adjust the new changes in her life, the team find themselves investigating a deadly fire at an arcade in Pennsylvania, leaving two dead and one severely injured. Gradually they discover that Fred Duncan, the father of the arcade's manager, hired two people to torch the place to gain insurance money in order to pay his son's gambling debt. Said two people are later found dead alongside two more victims, with the latter of which having a connection to Angelo Carpenter, who served 35 years in prison for a rape he never committed and is now seeking revenge against Fred Duncan, who was the real culprit. He kidnaps his granddaughter and returns them to the Duncan residence to re-enact said events. The Task Force surround the residence, but Carpenter attempts to escape, only to be shot by Ortiz. Hana connects with Ortiz, deciding to go to the bar with him.

• Tim DeKay (Angelo Carpenter) is credited as a Special Guest Star.

The team investigate when a prized Kentucky race horse is stolen with its groomer being taken hostage. They also learn that two murders at a country golf club and of the horse transport's driver came in addition as collateral damage. The groomer, Tessa Sanders, manages to convince Willy Burke, Solomon Pensky's accomplice, to let her go and work together to get the money demanded from the horse owner, Grace Roland, however she ditches him when the FBI is caught up on them. Initially Roland stonewalls the Task Force citing the demands of no law enforcement involvement, but is convinced by Barnes and Gaines. With the horse's return, Roland decides to let Sanders get away with the money, expressing that she earned it for her work with the horse. Byron, Jess's father returns to celebrate the holidays with Jess and Tali, while Jess also worries about the possibility of Tali getting accepted into a boarding school in Canada.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

A trip to the mall for some holiday shopping turns deadly for Jess and Barnes when they along with the other shoppers find themselves caught in the middle of a shooting with the exits being rigged with so that no-one can escape. Gibson, Ortiz and Gaines are notified and in turn is the NYPD, who works with them to defuse and locate the bombs and finding the mastermind behind it. On the inside, LaCroix and Barnes secures the former's family along with other shoppers in a staff room and work with former cop Linwood to disarm the shooters and find more survivors. A total of five bombs are discovered, but the fifth one remains of radar for the outside team until Ortiz discovers a timer at the mastermind, Rob Murphy's house. Linwood risks his life to save LaCroix and Barnes from the bomb while Byron assists Gaines and SWAT entry through the roof. With all bombs defused and shoppers evacuated, Charlotte, who was also trapped in the mall, goes into early labor and gives birth to a baby boy. Linwood is reunited with his son and LaCroix finds himself supporting Tali going to boarding school in Canada, with her application having been accepted.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

LaCroix and the Task Force search for Harley Ross, the abusive boyfriend of Lucy Carver, who killed Dr. Darien Johnson and his family in the search for her. They learn that Lucy sought sanctuary and protection from a covert website specialising in domestic abuse victims, and Ross continues his killing spree of people who would have insight to her whereabouts. They manage to save her handler, Alicia Dutton, while also learning that Lucy had a daughter, which triggered Ross. With intel from her, Ross goes to the ER to find their daughter, and sneaks out when the FBI surrounds him. LaCroix finds a bruised Lucy in the parking lot and shields her when Ross re-exits and shoots him, but is in turn killed by the other team members. Barnes and Gibson informs Sarah of LaCroix's passing, putting their travel plans on definite hold. Together, Sarah and Byron go to Canada to inform Tali of her father's death.

• This episode marks the final appearance of Jess LaCroix (Julian McMahon) while Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

Struggling to come to terms with Jess's death, Barnes, Hana, Ortiz and Gaines are given the assignment of tracking down a member of the incel community, Erik Perwin, who has begun embarking on a murder spree, targeting the people he believes never even gave him a chance. The incel community is in an uproar and another member, Jericho Brown, shoots up a saloon and seeks to work together with Perwin. They target a fashion show, where Perwin takes his idol model Chance Robbins hostage while Brown is shot when he brandishes his weapon. Gaines distracts Perwin, until Robbins breaks free himself and Ortiz subsequently tackles Perwin. Isobel Castille checks in on the team upon giving them the assignment, and the team decides to help Sarah finish the painted walls in her and Jess' home and share a meal with her and Byron.

• Terry O'Quinn (Byron LaCroix) is credited as a Special Guest Star.

When married couple Marianne and Will Conway, who grow illegal marijuana, kill their employees, the team head to Vermont to investigate and find the couple. Along the way, they learn that their operational application for marijuana has been rejected and that much of their personal information remain cryptic. Gibson and Gaines are trapped in their marijuana cellar when the couple returns home for seeds used as insurance, but Barnes frees them. From analogue records, they learn that Marianne is the daughter of Russian mobster Vasily Matrushok, whom they suspect ordered their daughter's kidnapping, only to learn that he retired longtime ago and left the mob's leadership to Marianne's sister Laura. Marinne and Will meet her at a secret marijuana site that Will set up, and she hands over their daughter in return for their seeds, but quickly goes back on her word just as the Task Force arrive and apprehend them all and securing the daughter. Barnes contemplates seeking maternity leave to be more present in her newborn son's life, which Castille accepts just as the CID's announcement of a new Task Force leader comes through.

• Alana De La Garza (Isobel Castille) is credited as a Special Guest Star.

The team are introduced to their new leader, Remy Scott, just as they begin to investigate the supposed abduction of teenage girl Lillie Jones. They soon learn that she went voluntarily along with her troubled boyfriend Jeremy Hamm as both their parents are found dead and later also a private investigator. Both Hamm and Jones have ties to the Covenant church and Intentions rehab facility, with the former in practise being a cult. When the pastor is found dead, they suspect his wife killed him as they learn from an undercover IRS agent that the church was suspected to be involved in tax evasion. Lillie is also revealed to be pregnant and scheduled to be married to Jeremy in a ceremony held by one of the rehab center's leaders Ken Clymer. On scene, Hamm is found dead and they track a rental vehicle to a motel, where Pat Mitchell, the pastor's wife, is arrested and Lillie saved. Scott invites the team out to throw axes and drink, and also shares the story of his brother Mikey.

• This episode marks the debut appearance of Remy Scott (Dylan McDermott)

In 1989, a notorious gangster is killed at a drive-by fast food chain by hitman Jackie "The Fox" Bianchi. In 2022, a mother and her two young sons are killed in a similar fashion at the same location. Shortly after, three people are killed at a funeral, again replicating a hit perpetrated by Bianchi. The Task Force enlist the help of Terry Daniels, the former lead investigator from Organised Crime in the case against Bianchi, to utilise inner mafia sources to get ahead of the copy cat, Joey Messina, who idolises Bianchi. Scott attempts to convince judge April Brooks to sign off on a warrant to retrieve info from Bianchi's podcast despite him being presumed dead in 1992. The application is denied, but the team deduce that Bianchi is alive and resides in Las Vegas based on a cooking video. Scott's ex-wife Carmen from the LVMPD aids in the raid and arrest of Bianchi. Brooks signs of on a revised deal for Bianchi's assistance to lure out Messina. Messina changes meeting locations, but Bianchi utilises him as a means to escape, but is arrested and Messina is gunned down after refusing to surrender. With encouragement from Carmen, Scott decides to seek out Brooks, whom he has developed a small fascination for.

• Wendy Moniz, as Judge Brooks, begins a short (4 episodes) run as a love interest for the character of Remy Scott.

When Cassandra Mason, a female con artist pretending to be a personal trainer murders a wealthy couple from the East Hamptons, she goes on the run and murders the ones she could expose her past. The Task Force are struggling to figure out her real identity, linking Jenny Bentz to a private school Treetops, who seemingly drowned at the school lake. Accounts from her mother confirms that Mason stole Bentz' identity, and her real name is revealed to be Dehlia Holby. She tries to borrow money from her sister, but is fruits when the amount is not enough, and takes her and her mother hostage. Through the Treetops principal's brother, a lawyer who helped settle a case against him about Dehlia's relationship with the former. It's because of this Dehlia has been doing what she has in order to escape her past. Scott talks her down and shoots her gun to disarm her. Ortiz is asked by Gibson's half brother George to lend him money to pay back a drug deal debt. Having considered his options, Ortiz ensures that George does pay him back by having him work at his local gym.

• This episode marks the final appearance of Ivan Ortiz (Miguel Gomez).

As the Fugitive Task Force meets FBI agent Ray Cannon, the team's newest member, they find themselves searching for a criminal who's targeting IRS offices in Tennessee. They learn that the now fugitive, Darla Crais, suffers from multiple personality disorder and has recently developed a third personality, which take the form of an abusive man. Another IRS agent is killed, and the Task Force learns that said agent and the first victim, was incrimated in a complaint at Cairs' workplace, also an IRS office, claiming they raped her during a conference in Colorado, however she later withdraw the complaint. In addition, it's revealed that Cairs was pregnant and likely didn't want to be registered for abortion because her DID could be revealed. Cairs takes the director of a clinic hostage in Atlanta, Georgia and attempts open her wound and get the baby out herself. The situation is diffused and Cairs is further treated. Both Barnes and Cannon experience difficulties with Scott, the former feeling she has been downgraded despite her longtime experience. Gibson advices Cannon to learn from his mistakes. Barnes and Scott agree that the latter should do better by her going forwards.

• This episode marks the debut appearance of Ray Cannon (Edwin Hodge).

The Fugitive Task Force and the New York field office work to secure the safety of the American President ahead of a UN speech, only to learn that he is in London. After rescuing HR manager Allison Green, the task force learns that her brother works for a security company which David Laporta once helped design, but deduces that the target is JFK airport. At the airport, the FBI works with the administration to localise possible target points, narrowed to the underground pipelines. Along the way, the New York office manages to apprehend Lenkov's closest associates, who were disguised as airport security, before they and the task force surround Lenkov himself, who refuses to disarm the bomb. Underground, Scott and Stuart Scola encountered a security guard who was unaware that all the terrorists were already captured. Tom Davidson thought that Scott and Scola were the "terrorists disguised as cops" and refused to get out of their way as they were running out of time to stop the bomb. Remy was forced to shoot him when he kept pointing his gun at them. They both managed to locate the bomb and deactivate it. However, the security guard later dies at the hospital.

The Task Force aid police in tackling a hostage situation at a bank, where Cannon sneaks in and tackles the suspect without shots being fired. They later help Scott in re-investigating his brother's case. Scott speaks to the witness, who reveals Mikey had fought with a fellow peer rather than a man. The witness is later found dead some time after Mikey's former friend Benji Piccagli goes on the run. The cop who spoke to the witness 25 years ago confirms the witness statement used in Davis' file is falsified, since he wrote it by hand, but also reveals that a girl was involved, who is identified as Jenna Marks. The Task Force arrest Benji's mother for aiding and abiding before she can kill Jenna. The Task Force board a train to Montreal, where Scott forces Benji to confess. He explains that he hit Mikey with a rock after they drunkenly argued about Jenna. Furthermore his parents helped him cover up the crime, framing Davis and his father bribing the DA into sentencing him. After Benji's arrest, Scott is informed that Davis has died. In Wade's documentary, he issues his apology to Davis. He also meets Jenna, who reveals she had travelled to Florida to inform Mikey that she was pregnant. Scott later goes to visit his nephew, Corey.

• This episode marks the final appearance of Kristin Gaines (Alexa Davalos)